核酸适体技术及其在生物毒素检测中的应用  

Technology and application in biotoxins detection of nucleic acid aptamer

作　　者：班珺 谢岩黎[1] 

机构地区：[1]河南工业大学粮油食品学院,河南郑州450052

出　　处：《粮食与油脂》2016年第8期76-79,共4页Cereals & Oils

基　　金：郑州市科技局新兴产业项目(20150503);河南省科技厅科技攻关项目(162102310084)

摘　　要：核酸适体是经指数富集配体系统进化技术(SELEX)从体外筛选出能与靶物质高亲和力、高特异性相结合的寡核苷酸片段。核酸适体因其众多优势在医学、生物、食品领域中迅速发展,对核酸适体技术及其近年来在生物毒素检测中的应用进行了综述。Nucleic acid aptamer is oligonucleotides which screen by systematic evolution of ligands by exponential enrichment （ SELEX ） in vitro and can bind to target molecules with high affinity and specificity. Nucleic acid aptamer has a lot of advantages and develop rapidly in the field of medical science, biology, food science. Nucleic acid aptamer and their applications of biotoxins detection in recent years were summarized.

关 键 词：核酸适体 生物毒素 安全检测 

分 类 号：TS207.3[轻工技术与工程—食品科学]