炎症性肠病发病机制研究进展  

Progress in Study on Pathogenesis of Inflammatory Bowel Disease

作　　者：曹婷[1] 曲波[1] 李惠[1] CAO Ting QU Bo LI Hui.(Department of Gastroenterology, the Second Affiliated Hospital of Harbin Medical University, Harbin （150001)

机构地区：[1]哈尔滨医科大学附属第二医院消化内科,150001

出　　处：《胃肠病学》2016年第9期569-572,共4页Chinese Journal of Gastroenterology

摘　　要：炎症性肠病(IBD)主要包括溃疡性结肠炎(UC)和克罗恩病(CD),是一组反复发作的慢性胃肠道炎症性疾病,其病因和发病机制至今尚未明确。目前观点认为IBD是环境因素、肠道菌群、个体易感性之间复杂作用的结果。本文就近年来研究较多的环境、感染、免疫、遗传因素在IBD中作用的新进展作一综述。Inflammatory bowel disease （IBD） is a group of chronic and recurrent inflammatory disorders of the gastrointestinal tract and is categorized into ulcerative colitis （UC） and Crohn＇ s disease （CD）. The etiology and pathogenic mechanism of IBD are not fully clear, however, it is generally accepted that IBD results from the complicated interactions between environmental factors and gut microflora in individuals who are genetically susceptible. In this article, progress in study on effects of environmental, infectious, immunological and genetic factors in IBD was reviewed.

关 键 词：炎症性肠病 环境 感染 免疫 遗传学 

分 类 号：R574[医药卫生—消化系统]