全切片图像在组织病理学同行评议和病理工作组中的应用  

Applications of Whole Slide Image in Peer Review of Histopathology and Pathology Working Group

作　　者：吕建军[1] 霍桂桃[1] 林志[1] 屈哲[1] 杨艳伟[1] 张頔[1] 张硕[1] 李波[2] 

机构地区：[1]中国食品药品检定研究院国家药物安全评价监测中心药物非临床安全评价研究北京市重点实验室,北京100176 [2]中国食品药品检定研究院,北京100050

出　　处：《中国药事》2016年第10期982-987,共6页Chinese Pharmaceutical Affairs

基　　金：科技部"十二五"重大新药创制专项课题(编号2012ZX09302001);"重大新药创制"科技重大专项课题(编号2015ZX09501007-004)

摘　　要：全切片图像与传统组织切片相比具有许多优势,广泛应用于教学、数字诊断、病理同行评议和病理工作组、科研及数字存档。本文简要介绍了全切片图像的定义、全切片图像的优点、全切片图像的缺点、全切片图像的用途、全切片图像用于病理同行评议的指导原则、全切片图像用于病理同行评议和病理工作组的优点、全切片图像用于病理同行评议和病理工作组的缺点等内容,以期为我国药物非临床安全性评价领域更好地将全切片图像用于组织病理学同行评议和病理工作组提供一定参考。Whole slide image（WSI） has many advantages compared to conventional tissue slides and is applied extensively, such as in education, digital diagnostics, peer review for histopathology and pathology working group（PWG）, research and digital archiving. The definition of WSI, advantages of WSI, disadvantages of WSI, applications of WSI, guildlines for the peer review by using WSI, advantages of WSI in peer review and PWG, and disadvantages of WSI in peer review and PWG, etc. were briefly introduced to provide some references for better application of WSI to peer review of histopathology and PWG during nonclinical safety evaluation of drugs in China.

关 键 词：药物非临床安全性评价 毒性病理学 组织病理学 同行评议 病理工作组 全切片图像 

分 类 号：R282[医药卫生—中药学] R95[医药卫生—中医学]