广西南宁地区新生儿G6PD缺乏症筛查情况分析  

Analysis of newborn G6PD defi ciency screening in Nanning

作　　者：罗超[1] 陈少科[1] 李旺[1] 林彩娟[1] 玉晋武[1] 耿国兴[1] 俸诗瀚[1] 

机构地区：[1]广西壮族自治区妇幼保健院儿童医院妇产医院,南宁530023

出　　处：《中国优生与遗传杂志》2016年第9期66-66,91,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解广西南宁市新生儿葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症筛查情况。方法采用荧光分析法检测2013年至2015年南宁市出生的新生儿筛查血样,并对不同性别,不同民族的新生儿G6PD缺乏情况进行分析。结果在筛查的101 782例新生儿中,有6240例缺乏G6PD,阳性率6.13%,不同性别和不同民族之间有统计学差异(P<0.05)。结论南宁市新生儿G6PD缺乏率较高,筛查有利于为该病提供早期诊断及预防。Objective：In order to know the result of newborn glucose-6-phosphate dehydrogenase（G6PD） deficiency screening in Nanning,Guangxi. Method：Fluorescence analysis method was used to measure newborn dried blood spot during 2013 to 2015 in Nanning,analyzed the G6 PD deficiency result of different gender and ethnic. Result：In total 101 782 newborns,6240 were G6PD deficiency,positive rate was 6.13%. Significant difference in different gender and ethnic（P〈0.05）. Conclusion：G6PD deficiency rate was high in Nanning,screening is benefit to early diagnosis and prevention.

关 键 词：葡萄糖-6-磷酸脱氢酶缺乏症 新生儿疾病筛查 南宁市 荧光分析法 

分 类 号：R722.1[医药卫生—儿科]