三种方式测量中央角膜厚度的对比研究  

Comparison of three methods of measuring the central cornea thickness

作　　者：杨雯[1] 廖志强[1] 

机构地区：[1]中国四川省成都市第三人民医院眼科,610031

出　　处：《国际眼科杂志》2016年第12期2305-2307,共3页International Eye Science

摘　　要：目的:比较使用A型超声角膜厚度测量计、眼前节光学相干断层扫描仪(OCT)和Allergro Oculyzer角膜地形图三种仪器测量中央角膜厚度的差异。方法:选取近视治疗中心就诊患者74例148眼,每位患者均使用A型超声角膜厚度测量计、眼前节光学相干断层扫描仪和Allergro Oculyzer角膜地形图三种仪器测量其中央角膜厚度。数据统计方式为组间两两比较使用配对t检验,组间的相关性使用Pearson相关性检验,组间测量方法的一致性采用Bland-altman方法。结果:A型超声角膜测厚、Allergro Oculyzer角膜地形图测厚、OCT角膜测厚的平均值分别为532.17±22.94、526.53±24.52、532.62±23.59μm。三种方式组间配对t检验。A型超声角膜测厚组与Allergro Oculyzer角膜地形图测厚组比较差异有统计学意义(P<0.05)。A型超声角膜测厚组与OCT角膜测厚组比较差异无统计学意义(P>0.05)。Allergro Oculyzer角膜地形图测厚组与OCT角膜测厚组比较差异有统计学意义(P<0.05)。线性相关性统计分析显示A型超声角膜测厚组、Allergro Oculyzer角膜地形图测厚组、OCT角膜测厚组两两呈正相关(r=0.972、0.964、0.973,P<0.05)。三种方式测量角膜厚度的一致性分析为具有较好的一致性。结论:A型超声角膜测厚、Allergro Oculyzer角膜地形图测厚、OCT角膜测厚三种测量方式对于CCT的测量具有明显的相关性和较好的一致性,临床上三种测量方式可以互为补充,相互参考。AIM：To compare central corneal thickness（ CCT） using Germany Allegro Oculyzer; Germany Heidelberg OCT Spectralis and Pachymetry SP-3000.METHODS： A total of 74 cases（ 148 eyes） were collected in the refractive surgery center in our hospital. The cornea thickness was measured by Germany Allegro Oculyzer;Germany Heidelberg OCT Spectralis and Pachymetry SP-3000 respectively. The difference of CCT was compared using t-test,the correlation and agreement was analyzed among the three methods with Pearson-test and Bland-Altman-test. Results： M ean CCT reading of Allegro Oculyzer;Heidelberg OCT Spectralis and Pachymetry SP- 3000 were532. 17±22. 94μ m,526. 53±24. 52μ mand 532. 62±23. 59μ m.The t- test showed difference between Allegro Oculyzer and Pachymetry SP-3000（ P〈0. 05）. There was significant difference between Allegro Oculyzer and Heidelberg OCT Spectralis（ P〈0. 05）. There was no significant difference between Heidelberg OCT Spectralis and Pachymetry SP-3000（ P〉0. 05）. There was significant linear correlation among the three methods（ r = 0. 972,0. 964,0. 973; P〈0. 05）. There was good agreement among the three methods. CONCLUSION： CCT measured by Allegro Oculyzer;Heidelberg OCT Spectralis and Pachymetry SP- 3000 have high correlation and agreement. The three methods are complement of each other. All can be used in measurement of CCT.

关 键 词：中央角膜厚度 鹰视眼前节分析诊断系统 海德堡光学相干断层眼前节扫描仪 A型超声 

分 类 号：R770.4[医药卫生—眼科]