卒中后抑郁患者交感神经皮肤反应特点及临床意义  

The characteristic of sympathetic skin response in post-stroke depression and the clinical significance

作　　者：王红艳[1] 李晶玉[1] 胡波[2] 李珊珊[1] 姜立刚[1] WANG Hong-yan LI Jing-yu HU Bo et al(Department of Neurology, Hospital Affiliated to Beihua University, Jilin 132001, China)

机构地区：[1]北华大学附属医院神经内科,吉林132011 [2]北华大学附属医院呼吸内科,吉林132011

出　　处：《临床神经病学杂志》2016年第6期413-416,共4页Journal of Clinical Neurology

基　　金：吉林省教育厅资助课题(吉教科合字2013第190号)

摘　　要：目的探讨卒中后抑郁(PSD)患者交感神经皮肤反应(SSR)的特点及临床意义。方法共采集脑卒中患者88例,根据汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)评分将脑卒中患者分为无抑郁组、轻中度抑郁组、重度抑郁组,选取22名健康人群作为健康对照组。各组患者分别进行SSR测定,记录首次达峰时间及SSR波幅并进行比较分析。结果本组脑卒中患者PSD发生率为67.05%,PSD组与健康对照组相比,SSR首次达峰时间延长;波幅减低(均P<0.05)。PSD组与无抑郁组相比,SSR首次达峰时间延长;SSR波幅减低(P<0.05)。重度抑郁组与轻中度抑郁组相比,SSR首次达峰时间延长;SSR波幅减低(均P<0.05)。结论 PSD患者SSR明显异常,抑郁越重,其异常程度越明显,SSR检测可有助于PSD诊断。Objective To explore the characteristic of sympathetic skin response （ SSR） in patients with post-stroke depression （ PSD） and the clinical significance .Methods Eighty-eight patients with stroke were evaluated by the Hamilton Depression Scale （ HAMD ） and the Self-Rating Depression Scale （ SDS ） , and divided into no depression group , mild to moderate depression group and severe depression group , 22 healthy people were introduced into control group .Their SSR was determined , and the first peaktime and amplitude of SSR .The results were compared and analyzed.Results The incidence of PSD was 67.05%in 88 stroke patients.The study group revealed prolonged first peak time and lower amplitude of SSR compared to control group and no depression group （ all P〈0.05）.The severe depression group exhibited a longer first peak time and a lower amplitude of SSR than mild to moderate depression group （ all P〈0.05 ） .Conclusions SSR in patients with PSD are abvious abnormality , the more serous the degree of depression in patients with PSD is , the more obvious the degree of abnormal .SSR may be helpful in diagnosis of PSD is .

关 键 词：交感神经皮肤反应 卒中后抑郁 脑卒中 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R749.4[医药卫生—临床医学]