迭代次数在宫颈癌术后调强放疗计划中对子野权重优化的影响  

The effect of iterative times on the segment weight optimization in IMRT plan of postoperative cervical cancer

作　　者：吴煜良[1] 何松美[1] 张纯[1] 吴伟艺[1] 崔顺景 赵艳海[1] 

机构地区：[1]广东省东莞市人民医院,东莞523000

出　　处：《实用肿瘤学杂志》2016年第6期507-510,共4页Practical Oncology Journal

基　　金：东莞市医疗卫生科技计划项目(20131051010111)

摘　　要：目的本研究主要探讨在宫颈癌术后调强放疗计划的设计过程中,选择不同的迭代次数,对子野权重优化(SWO)过程的影响。方法选择10例宫颈癌术后患者,采用CMS XIO 4.6.4治疗系统制定调强放疗计划。在SWO过程中,选择不同的迭代次数生成不同的计划,在不影响临床靶区剂量要求的前提下,比较其危及器官(OAR)受照剂量、子野数、机器跳数之间是否有差异。迭代次数选择以50为梯度,最高为300。结果对同一例患者,选择不同的迭代次数进行调强计划的SWO,对不同迭代次数的计划进行比较,股骨头、直肠、膀胱受照剂量基本没变化,计划总子野数和机器跳数变化不明显,差异无统计学意义(P>0.05)。结论在使用CMS XIO 4.6.4设计宫颈癌术后调强放疗计划过程中,100次以下的迭代次数进行SWO优化最为适合。可以在保证危及器官剂量、放疗总子野数和机器跳数基本不变的前提下,降低放疗计划设计时间从而提高工作效率。Objective To explore the use of Swedish medical company CMS 4.6.4 radiotherapy XIO system for the design process of cervical cancer postoperative IMRT plans in different iterative times of the same case,and to observe the Segment Weight Optimization（SWO） effect generated after the plan results.Methods Ten cases of cervical cancer patients were chosen,the use of XIO 4.6.4 CMS treatment system was performed for the development of the intensity modulated radiation therapy.In the SWO process,iterative times were used to generate different plans,without affecting the clinical dose target area requirements,and compared the organs at risk（OAR） by determining whether there were differences between dose and the number of segments,monitor units（MU）.Results For the same patients,different iterative times within a certain range of SWO IMRT plan were selected to compare the different iterative times plan,femoral head,rectum and the bladder dose did not change the basic plan.The total number of segments and MU did not change significantly（P〉0.05）.Conclusion IMRT plans in the use of CMS XIO 4.6.4 design of cervical cancer after operation in the process of using the iterative times below 100 times for SWO is the most suitable method for ensuring the organ dosimetry in radiotherapy.The total number of segments and the MU reduces the radiotherapy plan time so as to improve work efficiency.

关 键 词：迭代次数 子野权重优化 CMS XIO 宫颈癌术后 调强放射治疗计划 

分 类 号：R737.33[医药卫生—肿瘤]