煤矿地区早期老年痴呆认知功能障碍调查研究  

Early Alzheimer's Cognitive Disorder in Coal Region

作　　者：武增红 张燕[2] 侯亚平[2] 隽文琦 赵亚会[2] 尉杰忠[2] 吴花林[2] 

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北武汉430000 [2]山西大同大学医学院,山西大同037009

出　　处：《山西大同大学学报（自然科学版）》2016年第6期53-56,共4页Journal of Shanxi Datong University(Natural Science Edition)

基　　金：大学生创新创业项目[SDC2015006号]

摘　　要：目的通过随机检测煤矿地区老年人认知功能,旨在筛查和随访早期认知功能障碍者,为临床早期老年痴呆症(AD)的诊断提供依据。方法随机抽取大同煤矿地区医院的60岁以上住院患者以及医疗体检中心60岁以上常规体检人员104例,通过简易精神状态评价量表(MMSE)进行筛查和随访。结果患有认知功能障碍的有68例(65.4%),其中轻度占31例(29.8%),中度占36例(34.6%),重度占1例(0.01%)。可以得出学历和年龄对认知功能障碍的发生有一定的统计学意义(P<0.01);其中年龄、文化程度、是否脑梗死3个自变量在排除了其他变量的影响后,均对认知障碍有显著影响(P<0.01)。结论文化程度的高低、年龄的大小、脑梗死与煤矿地区早期AD的发生有一定的关联性,为临床早期预防、诊断AD提供一定数据。Objective random testing of cognitive function in old people in coal mines,aimed at screening and follow-up of early cognitive impairment,provide the basis for early clinical Alzheimer’s disease（AD） diagnosis.Methods Datong Coal Mine randomly selected regional hospital inpatients over the age of 60 medical centers and medical routine medical staff over the age of 60,by the Mini Mental State Evaluation Scale（MMSE）,screening and follow-up.Results 104 investigation reports from the scores of MMSE results,suffering from cognitive impairment,68 patients（65.4%）,mild possession of 31 patients（29.8%）,moderate possession of 36 cases（34.6%）,severe occupy one case（0.01%）.The patient relationship between cognitive impairment using chi-square test method can be drawn education and age occur cognitive dysfunction have some statistical significance（P〈0.01）;while using logistic regression analysis draw,where age,educational level,whether cerebral infarction three arguments to exclude the effects of other variables,the have significant effects on cognitive impairment（P〈0.01）.Conclusion Based on the 104 investigation reports show,size age,the size of the education level,infarction and the occurrence of coal mine area early AD have some relevance for clinical early prevention,diagnosis AD provide some data.

关 键 词：老年痴呆症 MMSE 早期认知功能障碍 

分 类 号：R742[医药卫生—神经病学与精神病学]