小牛血去蛋白提取物眼用制剂临床应用评价  

Review of Clinical Application of Deproteinized Extract of Calf Blood Ophthalmic Preparation

作　　者：张卫鹏[1] 陈曦[1] 王晓娜[2] 刘美欣[1] ZHANG Wei-peng CHEN Xi WANG Xiao-na LIU Mei-xin(Tianjin Eye Hospital, Ocular Trauma Department, Tianjin Laboratory of Eye and Visual Science, Tianjin Ophthalmic Research Institute, Tianjn Medical University, Tianjin 300020, China Tianjin Medical University General Hospital)

机构地区：[1]天津市眼科医院眼外伤科,天津市眼科学与视觉科学重点实验室,天津市眼科研究所,天津医科大学眼科临床学院,天津300020 [2]天津医科大学总医院

出　　处：《中国城乡企业卫生》2017年第1期40-43,共4页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：小牛血去蛋白提取物(DECB)是指从幼牛静脉血中提取分离纯化后的小分子混合物生物制品,已经被证实在多种疾病的治疗中均有很好的疗效。DECB眼用制剂在临床应用历史已有40多年的历史近年来,DECB的临床应用范围不断扩大且存在多种剂型和给药方式在眼科同样存在这种现象因此论文采用对国内外相关文献综述的方法,对DECB眼用制剂在眼科临床应用的历史和最新进展以及DECB的作用机制进行概述,以便医务工人员理论联系实际,在积极为患者开拓更有效的治疗手段的同时,密切关注药品质量,为患者的用药安全把好每一道关,为其临床合理用药及联合应用提供参考和依据。Deproteinized extract of calf blood（DECB） has been proven to be an effective biological product in the treatment of many diseases.DECB eye preparation in clinical application has a over 40 years history,in recent years,the clinical application of DECB continues to expand,and there are a variety of forms and administration ways,this phenomenon also exists in the ophthamic.In this review,we would like to summarize the history of DECB ophthalmic preparation and recent findings in clinical application and the mechanism.In order to develop a more effective treatment,and the same to pay close attention to drug quality for the patients safety.And to provide solid evidence to promote the clinical rational drug use.

关 键 词：小牛血去蛋白提取物 眼科 临床应用 药物安全 生物制品 

分 类 号：R77[医药卫生—眼科]