左旋葡聚糖的制备与在生物技术领域的应用  

Preparation of Levoglucosan and Its Applications in Biotechnology

作　　者：李文惠[1] 武红丽[1] 黄婷[1] 邓茹[1] 曹飞[1] 韦萍[1] 

机构地区：[1]南京工业大学生物与制药工程学院江苏省工业生物技术重点实验室,南京211816

出　　处：《化学通报》2017年第3期251-259,共9页Chemistry

摘　　要：左旋葡聚糖(LGA)作为一种极具潜力的新糖源,既可以加酸水解为葡萄糖后间接用于微生物发酵,也可以被真菌或细菌甚至构造的基因工程菌直接代谢,目前已经在发酵上展现出良好的应用前景。此外,LGA还可作为碳源,生产生物乙醇、丁二酸等。目前制备LGA普遍采用生物质热解法,该方法存在能耗高、产率低、产物难以提取等缺点,应努力发展在溶剂体系中分解纤维素制备LGA的方法以提高产率。今后的研究应致力于开发微生物代谢LGA的新过程、新方法、新菌种,为LGA的高效利用提供坚实基础。Levoglucosan is a potential source of sugar,it can be hydrolyzed into glucose and then used for microbial fermentation,or be directly metabolized through levoglucosan kinase or levoglucosan dehydrogenase in some fungi and bacteria.It showed a good application prospect in the fermentation field.In addition,levoglucosan can also be used as a carbon source to produce bio-ethanol,succinic acid and so on.At present,biomass pyrolysis is the common-use preparation method of levoglucosan.However,this method has the disadvantages of high energy consumption,low yield and difficult to extract the product.In order to improve the yield of levoglucosan,we should strive to develop a method of decomposing cellulose in solvent system.Future researches should focus on the development new processes,new methods,and new strains for microbial metabolism of levoglucosan,which could lay the groundwork for the efficient use of levoglucosan.

关 键 词：左旋葡聚糖 生物质 微生物发酵 碳源 

分 类 号：O636.1[理学—高分子化学]