飞扬草中酚类成分的分离与鉴定  

Isolation and Identification of Phenolic Chemical Constituents from Euphorbia hirta L.

作　　者：杨光忠[1] 石宽[1] 甘飞[2] 吴士筠 杨文婷 陈玉[2] Yang Guangzhong Shi Kuan Gan Fei Wu Shijun Yang Wenting Chen Yu(School of Pharmaceutical Science, South-Central University for Nationalities,Wuhan 430074, China College of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan 430074,China College of Environmental and Biological Engineering, Wuhan Technology and Business University, Wuhan 430065,China)

机构地区：[1]中南民族大学药学院,武汉430074 [2]中南民族大学化学与材料科学学院,武汉430074 [3]武汉工商学院环境与生物工程学院,武汉430065

出　　处：《中南民族大学学报（自然科学版）》2017年第1期43-46,共4页Journal of South-Central University for Nationalities：Natural Science Edition

基　　金：国家自然科学基金资助项目(31370379)

摘　　要：为研究飞扬草中的酚类化学成分,利用溶剂提取法,正、反相硅胶柱和半制备高效液相色谱法对其进行了分离纯化,并根据理化性质和波谱技术对其进行了结构鉴定.从飞扬草乙酸乙酯提取物中分离得到了12个酚类化合物,分别鉴定为木犀草素(1)、槲皮素(2)、3'-甲基杨梅黄酮(3)、松脂酚(4)、4-ketopinoresinol(5)、3,4-二羟基苯甲酸(6)、咖啡酸(7)、香草酸(8)、丁香酸(9)、没食子酸乙酯(10)、橙黄胡椒酰胺乙酸酯(11)、橙黄胡椒酰胺(12),其中化合物3、5、8、10~12为首次从飞扬草中分离得到.To study the phenolic chemical constituents of Euphorbia hirta L.,the chemical components were isolated and purified by solvent extraction,followed by normal and reverse phase silica gel column chromatography and semi-preparative HPLC. The structures of the isolated compounds were elucidated on the basis of chemical and spectroscopic analysis.Twelve compounds were isolated from the ethyl acetate extract of Euphorbia hirta L. and were identified as luteolin（1）,quercetin（2）,larycitrin（3）,pinoresinol（4）,4-ketopinoresinol（5）,3,4-dihydroxy-benzoic acid（6）,caffeic acid（7）,vanilic acid（8）,syringate（9）,ethyl gallate（10）,aurantiamide acetate（11）,aurentiamide（12）. Among these,compounds 3,5,8,10-12 were isolated from this plant for the first time.

关 键 词：飞扬草 化学成分 酚类化合物 

分 类 号：Q629[生物学—生物物理学] R914.4[医药卫生—药物化学]