1997—2011年中国成年居民腰围变化对血压影响的队列研究  

A cohort study of the association between waist circumference changes and blood pressure among Chinese adults in 1997 - 2011

作　　者：曹婷婷[1] 杜文雯[1] 苏畅[1] 王惠君[1] 王志宏[1] 欧阳一非[1] 张兵[1] 

机构地区：[1]中国疾病预防控制中心营养与健康所,北京100050

出　　处：《卫生研究》2017年第2期179-183,共5页Journal of Hygiene Research

基　　金：中国健康与营养调查(No.R01-HD30880;DK056350;R01-HD38700)

摘　　要：目的探讨中国成年居民腰围变化对血压及高血压发病的影响。方法利用"中国健康与营养调查"数据,选择参加1997年调查并且在2011年被随访到的有完整体格测量资料的18~65岁成年居民为研究对象。运用多元线性回归模型分析腰围变化对血压值的影响,运用Logistic回归模型分析腰围变化对高血压发病的影响。结果与1997年比较,2011年中国18~39岁年龄组男性和女性腰围分别增加9.1和7.8 cm,40~65岁年龄组分别增加5.5和6.6 cm,18~39岁年龄组均较40~65岁年龄组增加明显,差异有统计学意义(P<0.05)。多元线性回归结果显示,18~39岁成年居民腰围变化与收缩压和舒张压变化有正向关系,且与收缩压变化关系较舒张压变化明显;而在40~65岁成年居民中,腰围变化与舒张压变化关系显著。Logistic回归结果显示,当腰围变化作为连续性变量进入模型时,腰围每增加1 cm,18~39岁年龄组和40~65岁年龄组高血压的发病风险分别增加5%和4%;当腰围变化以四分位数形式进入模型时,第四分位与第一分位相比,高血压的发病风险明显增加(18~39岁年龄组OR=2.56,95%CI 1.56~4.22;40~65岁年龄组OR=2.84,95%CI 1.77~4.57)。结论腰围变化与血压变化存在正相关关系,18~39岁年龄组较40~65岁年龄组显著,前者主要作用于收缩压变化,后者主要作用于舒张压变化,腰围增加可显著增加高血压的发病风险。Objective To explore the association between waist circumference（ WC）changes and blood pressure and the risk of developing hypertension. Methods The data were collected from the China Health and Nutrition Survey. Subjects aged 18-65 years with complete anthropometric data in 1997 and followed up in 2011 were included in the study. Multiple linear regression model were used to analysis the association between WC changes from 1997 to 2011 and blood pressure,logistic regression model were used to analysis the association between WC changes from 1997 to 2011 and the risk of developinghypertension. Results Compared with 1997,WC increased by 9.1 cm and 7.8 cm for men and women of the 18-39 age group,5.5cm and 6.6cm of the 40-65 age group in2011,respectively. The 18-39 age group increased more than the 40- 65 years age group and the difference was significant（P 0.05）. Multiple linear regression analysis showed that changes in WC had a positive correlation with changes in systolic blood pressure（SBP） and diastolic blood pressure（DBP） in the 18- 39 age group. The relationship was more significant with SBP in 18- 39 age group and with DBP in 40- 65 age group. Logistic regression results showed that when WC changes were included as continuous variables,for a 1 cm increase in WC,the risk of hypertension increased by5% and 4% for the 18- 39 age group and the 40- 65 age group respectively. When WC changes were included as quartiles, the risk of hypertension in the fourth quintile increased significantly compared with the first quintile（18-39 age group OR = 2.56,95% CI 1. 56-4.22,40-65 age group OR =2.84,95% CI 1.77- 4. 57）. Conclusion There is a positive correlation between changes in WC and in blood pressure which is more significant in the 18-39 age group than in the 40-65 age group. WC changes are more relevant with SBP in the 18- 39 age group and with DBP in the 40- 65 age group.WC changes can significantly increase the risk of hypertension.

关 键 词：成年居民 腰围 收缩压 舒张压 高血压 队列研究 

分 类 号：R151.41[医药卫生—营养与食品卫生学] R181.37[医药卫生—公共卫生与预防医学]