SPECT/CT影像技术用于阿尔兹海默症患者诊断的临床价值分析  

Clinical value analysis of SPECT/CT technique in diagnosis of Alzheimer's disease

作　　者：张勇[1] 刘小莉[1] 郭利锋[1] 

机构地区：[1]郑州市第三人民医院,河南郑州450000

出　　处：《中国民康医学》2017年第2期4-5,8,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:研究SPECT/CT独立用于阿尔茨海默病(AD)患者诊断的临床价值。方法:将23例AD患者设为研究组;另将20例正常人作为对照组。对两组研究对象进行SPECT/CT检查,并对比分析其局部脑血流量(r CBF)、达峰时间(TTP)、额叶达峰时间、颞叶达峰时间、基底节达峰时间和海马达峰时间,研究上述指标与AD患者的相关性。结果:研究组患者的r CBF显著低于对照组(P<0.05),TTP、额叶达峰时间、颞叶达峰时间、基底节达峰时间和海马达峰时间均显著高于对照组(P<0.05)。结论:采用SPECT/CT技术对研究对象脑血流灌注情况监测,独立用于AD患者的临床诊断具有可行性。Objective： To study clinical value of SPECT/CT technique in independent diagnosis of Alzheimer＇s disease. Methods： 23 cases of patients with AD were set as study group and 20 cases of normal people were used as control group. The subjects of the two groups accepted the SPECT/CT examination,and the values of regional cerebral blood flow（ r CBF）,time to peak（ TTP）,and time to peak of frontal lobe,temporal lobe,basal ganglia and hippocampi were recorded. Then the relevance of these parameters and AD was studied. Results： The value of r CBF of the study group was significantly lower than that of the control group（ P〈0.05）,meanwhile,the values of the rest parameters were significantly higher than thoseof the control group（ P〈0.05）. Conclusions： It is feasiblefor the independent diagnosis of Alzheimer＇s disease with the SPECT/CT technique.

关 键 词：SPECT/CT AD 临床诊断 

分 类 号：R741[医药卫生—神经病学与精神病学]