Supported by National Natural Science Foundation of China(82160832);Natural Science Foundation of Guangxi Zhuang Autonomous Region(2022GXNSFAA035603&2017GXNSFAA198255);the Open Project Program of Guangxi Key Laboratory of Brain and Cognitive Neuroscience,Guilin Medical University(GKLBCN-202206-02);the Fourth Training Plan of Thousands of Young and Mid-aged Mainstay Teachers in Guangxi Colleges and Universities.
[Objectives]To explore the possible targets of Huanglian Jiedu Decoction in NLRP3/IFITM3/γ-secretase pathway through regulating iron homeostasis and the potential mechanism of anti-Alzheimer s disease(AD).[Methods]Fi...