复方三黄酊体外抑菌活性的研究  

Study of bacteriostatic action in vitro of compound sanhuang tincture

作　　者：丁长玲[1] 田洪根 张学美 樊其忠[1] 

机构地区：[1]滨州医学院附属医院药学部,滨州256603 [2]滨州市食品药品检验检测中心 [3]滨州市妇幼保健院

出　　处：《滨州医学院学报》2017年第2期134-136,共3页Journal of Binzhou Medical University

基　　金：滨州市科技计划课题(2014ZC0146)

摘　　要：目的评价两种不同工艺制备的抗感染药物复方三黄酊的体外抗菌活性。方法采用抑菌圈试验和胰酪大豆胨液体培养基稀释法对大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌、沙门氏菌和白色念珠菌进行体外抑菌试验,进行了最低抑菌浓度(MIC)和最低杀菌浓度(MBC)的试验研究。结果两种工艺制备的抗感染药物复方三黄酊对金黄色葡萄球菌、铜绿假单胞菌和白色念珠菌具有较强的抑菌和杀菌活性,以金黄色葡萄球菌较为敏感。结论本院生产的抗感染药物复方三黄酊具有明显的体外抑菌活性。Objective To study the bacteriostatic action invitro of two kinds of preparation technology of compound Sanhuang tincture in vitro. Methods To use the bacterial inhibition ring assay and the pancreatic dairy soy peptone liquid medium diluted method to do minimal inhibitory concentration （MIC） and minimal bacterieidal concentration （MBC） test for Escherichia coil, Staphylococcus aureus,Pseudomonas aeruginosa, and Candida albicans. Results Two preparation process of compound San- huang tincture has strong bacteriostatie and bactericidal activity of the Staphylococcus aureus, Pseudomonas aeruginosa and Candida albieans,Staphylococcus aureus is more sensitive. Conclusion The compound sanhuang tincture had remarkable bacteriostatic action in vitro.

关 键 词：抗感染药物 复方三黄酊 抑菌 杀菌 浓度 

分 类 号：R969[医药卫生—药理学]