宝鸡地区高龄孕妇产前诊断探讨  

Study on the prenatal diagnosis of elderly women in Baoji district

作　　者：张树琪[1] 张娟玲[2] 唐凯[2] 成艳[2] 韩凯[2] 权秋宁[2] 刘郁明[2] ZHANG Shu-qi ZHANG Juan-ling TANG Kai CHENG Yan HAN Kai QUAN Qiu-ning LIU Yu-ming(Baoji city Chinese Traditional Medicine Hospital, Shaanxi Province 721001 Baoji Maternity and Child Health Care Hospital, Shaanxi Province 721099)

机构地区：[1]陕西省宝鸡市中医医院,721001 [2]陕西省宝鸡市妇幼保健院,721099

出　　处：《中国优生与遗传杂志》2017年第4期92-92,112,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的研究与探讨宝鸡地区高龄孕妇在超声引导下进行羊膜腔穿刺术的产前诊断的安全性及应用价值。方法回顾性分析宝鸡地区2014年1月至2016年11月之间进行羊膜腔穿刺术的高龄孕妇共210例,羊水细胞进行培养分析后,对产前诊断结果、妊娠结局及流产率进行分析。结果与结论共发现异常核型14例,异常核型检出率为6.67%,其中数目异常8例,占异常核型3.81%,结构异常6例,占异常核型2.86%,穿刺术后均无流产、无其他穿刺并发症发生。Objective：To study the safety and value of ultrasound-guided prenatal diagnosis of amniocentesis in elderly women in Baoji area. Methods：A retrospective analysis of amniocentesis among the elderly 210 cases of pregnant women of Baoji in January 2014 to November 2016,amniotic fluid cell culture analysis,the prenatal diagnosis,pregnancy outcome and abortion rate were analyzed. Results and Conclution：Abnormal karyotype was found in 14 cases and abnormal karyotype in 6.67%. The number of abnormal karyotypes was 8 case,accounting for 3.81% of abnormal karyotype and 6 case of structural abnormality,accounting for 2.86% of abnormal karyotype.No abortion after puncture and no other complications of puncture.

关 键 词：高龄孕妇 染色体异常 羊膜腔穿刺 产前诊断 

分 类 号：R714.5[医药卫生—妇产科学]