肝纤维化与Wnt信号转导通路及该通路干预研究现状  

Status of Liver Fibrosis and Wnt Pathways and Its Pathways' Intervention

作　　者：李博[1] 张寿文[1] 程波翔 董燕婧 蒋伟[1] 

机构地区：[1]江西中医药大学中药资源与民族药研究中心,江西南昌330004

出　　处：《中华中医药学刊》2017年第5期1174-1176,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81360675)

摘　　要：肝纤维化的发病机制较为复杂,目前Wnt信号转导通路与肝纤维化的研究引起了广大学者的关注。通过文献查阅综述了Wnt信号在肝纤维化过程中的作用及该通路干预抗肝纤维化,为此指出了关于该通路研究空白,这可能将为揭示肝纤维化的发病机制及其干预治疗提供可能的研究方向,并可能为临床治疗诊断肝纤维化提供理论基础。The pathogenesis of liver fibrosis is relatively complex and the study on Wnt signaling pathway and liver fi- brosis has been occupied the eyes of many scholars. This article summarized the role of Wnt signaling in liver fibrosis process and the channel interference resisting hepatic fibrosis by literature review and pointed out the research on the pathway tor this gap, which could be for revealing the pathogenesis of hepatic fibrosis and its intervention to provide possi- ble research direction, and may provide a theoretical basis for clinical diagnosis of liver fibrosis.

关 键 词：肝纤维化 WNT HSCS 

分 类 号：R575[医药卫生—消化系统]