非酒精性脂肪性肝病的非药物治疗  

Non-pharmacological interventions in non-alcoholic fatty liver disease patients

作　　者：李薇[1] 何卫平[2] 

机构地区：[1]中华医学会,北京100710 [2]解放军第三0二医院肿瘤放射治疗中心,北京100039

出　　处：《中华健康管理学杂志》2017年第3期269-272,共4页Chinese Journal of Health Management

摘　　要：非酒精性脂肪性肝病患者常常有不健康的饮食习惯、久坐行为和不充分的体育锻炼，这种生活方式会诱发肝脏疾病并不断进展，也是导致终末期肝病和肝细胞癌的一个重要病因。本文从非药物治疗的视角，探讨了生活方式的调节，包括饮食控制、体育锻炼和减重仍然是最有效的治疗方式，对于通过生活方式调节没有达到减重目标的肥胖患者，减重手术改善了肝脏的脂肪变性、炎症和纤维化。综合治疗措施能产生协同效应，但长期坚持尤为关键。Patients with non-alcoholic fatty liver disease （NAFLD） have unhealthy diets, sedentary behavior and lack of physical activity. This lifestyle triggers liver disease and probably favors its progression. It is now the most common significant cause of end-stage liver disease and hepatocellular carcinoma. From the perspective of non-pharmacological intervention, lifestyle modifications including diet, exercise, and weight loss remain the most effective therapy for nonalcoholic fatty liver disease. Bariatrie surgery in morbidly obese individuals who have failed to lose weight through lifestyle modifications can improve steatosis, inflammation, and fibrosis. Comprehensive treatment measures can produce synergistic effect, but long-term adherence is particularly critical.

关 键 词：膳食 减重 身体锻炼 非酒精性脂肪性肝病 

分 类 号：R575.5[医药卫生—消化系统]