拔牙创不同处理方式对牙槽窝愈合影响的实验研究  

The effects of different treatments of tooth extraction wound on alveolar bone healing

作　　者：孙旭[1] 董福生[1] 任贵云[1] 李宁[1] 张旭东[1] 

机构地区：[1]河北医科大学口腔医院,石家庄050000

出　　处：《实用口腔医学杂志》2017年第4期557-559,共3页Journal of Practical Stomatology

基　　金：河北省医学适用技术跟踪项目(编号:GL201354)

摘　　要：拔除36只兔的双侧下颌第一磨牙,拔牙创处理分为4组(n=9),A组:PRF联合ADM组;B组:PRF组;C组:ADM组;D组:对照组。不同时间点牙槽骨高度与宽度比较各组间差异无显著性(P>0.05);骨计量学各参数比较:术后2、4周各组之间比较有统计学意义(P<0.01),A组最优;术后8周B组与C组差异无显著性(P>0.05),A组分别与另2组比较有统计学意义(P<0.01),A组最优。PRF联合ADM促进拔牙窝愈合效果最佳。Bilateral mandibular first molars of 36 rabbits were extracted. The tooth extraction wounds were treated by： platelet-rich fibrin ＋ acellular dermal matrix（ group A）, platelet-rich fibrin（ group B）, acellular dermal matrix（ group C） and without treatment（ group D, the control） （n = 9） respectively. The measurments of alveolar bone height and width showed that there were no significant differences among groups at different times（P 〉0.05）. Bone histomorphometry showed that at the 2th and 4th week, the best result was found in group A（P 〈 0.01 ）. While, at the 8th week, the result of group A was still better than that of other 3 ones （ P 〈0. 01 ）, but group B and C showed no sig- nificant difference（P 〉0.05）. The combination of PRF and ADM shows the most significant effect.

关 键 词：拔牙创 富血小板纤维蛋白(PRF) 脱细胞真皮基质组织补片(ADF) 骨组织形态计量学 

分 类 号：R782.11[医药卫生—口腔医学]