首发精神分裂症患者恐惧表情识别特征的对照研究  

A comparative study on the characteristics of fear expression recognition in the first-episode schizophrenia

作　　者：齐安思 杨程青[2] 刘娜[2] 朱俊娟[2] 黄楠 徐逸 张洁[2] 管晓波[3] 刘飞[1] 管晓枫 龙翔云[1] 陆峥[1,2] 

机构地区：[1]同济大学附属同济医院精神医学科,上海200065 [2]上海交通大学医学院附属精神卫生中心 [3]上海市民政第三精神卫生中心

出　　处：《国际精神病学杂志》2017年第4期585-588,共4页Journal Of International Psychiatry

基　　金：国家重点研发计划(编号:2016YFC1306805);国家自然科学基金(编号:81471359);上海市科委中西医引导项目(编号:14411963400);上海市重中之重临床重点学科(编号:2017ZZ02020)

摘　　要：目的探讨首发精神分裂症患者恐惧表情识别的特征。方法采用病例对照研究,对性别、年龄、文化程度匹配的精神分裂症首次发病患者组(27例)和对照组(28名),应用Ekman标准表情库研究两组受试者对高度恐惧和低度恐惧表情识别的总体应答率、低度恐惧和高度恐惧的准确率和反应时间。结果病例组的高度恐惧准确率(50.41±6.18)低于对照组(68.29±4.27,P=0.034)。健康对照组低度恐惧的反应时间(362.84±25.23)与准确率(21.79±2.28)呈正相关(r=0.494,P=0.008),病例组阴性症状分(23.35±10.56)与高度恐惧准确率呈负相关(r=-0.428,P=0.042)。结论首发精神分裂症患者在高度恐惧面孔表情中存在识别障碍,对于恐惧表情识别准确率可以反映患者的阴性症状。Objective To investigate the characteristics of fear expression recognition in the first-episode schizophrenia patients. Methods Adopting case-control design,this study using Ekman facial expression of emotion base investigate high and low level fear recognition ability in 27 first-episode schizophrenia patients and 28 healthy controls with matching sex,age and educational level,analyse general response rate of facial expression emotion,correct rate of high and low fear recognition and its response time. Results The patients＇ high level fear recognition accurate rate（50.41±6.18）was lower than that of the control group（68.29±4.27,P=0.034）. The response time of the low level fear in the healthy control group（362.84±25.23）was positively correlated with the accuracy rate（21.79±2.28）（r=0.494,P=0.008）. The patients＇ negative score of PANSS（23.35±10.56）was negatively correlated with the accuracy of high level fear recognition（r =-0.428,P=0.042）. Conclusion First-episode schizophrenia patients have high level fear recognition disorder,which indicates that fear recognition ability reveals the negative symptoms of firstepisode schizophrenia patients.

关 键 词：首发精神分裂症 表情识别 反应时间 恐惧表情 

分 类 号：R749.3[医药卫生—神经病学与精神病学]