几种常见饮料作口服阴性对比剂在MRCP检查中的可行性分析  

Analysis on feasibility of several common beverages as oral negative contrast agents in MRCP examination

作　　者：黄兴涛[1] 肖明盛 谭炜[1] 吴媛[1] 梁秀梅[1] 祁磊[1] 刘德素 

机构地区：[1]重庆市第五人民医院放射科,400062 [2]重庆市第五人民医院普外科,400062

出　　处：《检验医学与临床》2017年第17期2518-2520,共3页Laboratory Medicine and Clinic

基　　金：重庆市南岸区卫生和计划生育委员会医学科研计划项目(2013276)

摘　　要：目的探讨几种常见饮料在磁共振胰胆道成像(MRCP)中降低胃肠道液体干扰的可行性。方法 (1)体外试验:将10种不同品牌的饮料及4种不同浓度(4、6、8、10g/150mL)的绿茶分别盛入14支20mL注射器内,以纯净水作为参照物,然后行MRCP扫描,筛选出对降低胃肠道液体干扰最明显的饮料用于临床试验。(2)临床试验:对12例健康志愿者于口服绿茶前、口服绿茶后10min行MRCP扫描,观察并比较胃、十二指肠信号丢失情况及胆道系统图像质量。结果 (1)体外试验显示几种常见饮料中,4种不同浸泡浓度的绿茶对降低胃肠道液体干扰最明显,考虑到口感因素,故选择4g/150mL的绿茶用于临床试验。(2)12例健康志愿者口服绿茶后10min胃、十二指肠信号丢失,胆总管、胆胰壶腹、胰管及胆囊的图像质量均优于口服绿茶前(P<0.05)。结论绿茶作为一种安全、廉价、易获取、口感好的饮料,能够降低胃肠道液体对MRCP图像质量的影响,可应用于临床。Objective To investigate the feasibility of several common beverages for reducing gastrointestinal fluid interference in magnetic resonance cholangiopancreatography（MRCP）.Methods（1）The in vitro test：10 different beverages and 4 different concentrations（4,6,8,10g/150 mL）of green tea were filled into 14 20 mL syringes,and then were scanned by MRCP with purified water as the reference substance.The beverage of most obviously reducing the interference of gastrointestinal fluid was screened out for clinical trial use.（2）Clinical trial：12 volunteers were scanned by MRCP before drinking green tea and at 10 min after drinking green tea.The signal loss situation of stomach and duodenum,and the image quality of biliary system were observed and compared between before tea drinking and at 10 min after tea drinking.Results（1）The in vitro test showed that among 4different beverages,the green tea of 4 different concentrations could most obviously reduce the interference of gastrointestinal fluid.Taking the taste into account,the green tea of 4g/150 mL concentration was selected to be use in the clinical trial.（2）The signals of stomach and duodenum were lost at 10 min after tea drinking and the image quality of common bile duct,ampulla of vater,pancreatic duct and gall bladder was superior to that before tea drinking（P0.05）.Conclusion As a safe,cheap,easily accessible and good-tasting beverage,the green tea can decrease the influence of gastrointestinal fluid on the image quality of MRCP and can be used in clinic.

关 键 词：磁共振胰胆管成像 对比剂 绿茶 

分 类 号：R575[医药卫生—消化系统]