左乙拉西坦治疗小儿癫痫110例疗效及对患儿生活质量的影响  

Study on the treatment effect of levetiracetam for 110 children with epilepsy and the effect on the quality of life

作　　者：徐晓科[1] 王治静[1] 汪东[1] 赵斯钰[1] 张艳[2] 

机构地区：[1]西安市儿童医院神经内科,西安710003 [2]西安市第四医院儿科,西安710004

出　　处：《陕西医学杂志》2017年第9期1268-1269,1290,共3页Shaanxi Medical Journal

摘　　要：目的:探讨左乙拉西坦治疗小儿癫痫的有效性、安全性及对患儿生活质量的影响。方法:将220例小儿癫痫患者根据其治疗方式分为两组,观察组110例患者使用左乙拉西坦治疗,对照组110例患者使用丙戊酸钠治疗,观察并比较两组患者的治疗效果。结果:(1)观察组患者治疗有效率为95.45%,明显高于对照组的79.09%(P<0.05);(2)治疗前,两组患者认知功能评分无统计学差异(P>0.05),而治疗后,观察组上述指标值明显高于对照组(P<0.05)。结论:左乙拉西坦治疗小儿癫痫,提高患者认知功能,改善其生活质量,治疗安全有效。Objective： To study on the efficiency and safety of levetiracetam in the treatment process of epilepsy for children and the effect on the quality of life.Methods： The 220 children with epilepsy were divided into observation group and control group according to different methods.The patients were treated with levetiracetam in the observation group （n =110）, while the patients were treated with sodium valproate in the control group （n =110）.The treatment effects were observed and compared.Results： ①The effective rate in the observation group was 95.45%, which was significantly higher than 79.09% in the control group patients （P〈0.05）.②There was no significant difference between these two groups about the score of cognitive function before treatment （P〉0.05）.After treatment, the values of index in the observation group were higher significantly （P〈0.05）.Conclusion： Levetiracetam is used to children with epilepsy, and it strengths the cognitive function of patients with improved their quality of life.The treatment is safe and effective.

关 键 词：癫痫/药物疗法 抗惊厥药/治疗应用 @生活质量 

分 类 号：R742.1[医药卫生—神经病学与精神病学]