Palladium-Catalyzed Intermolecular Oxidative Diazidation of Alkenes  

作　　者：Haihui Peng Zheliang Yuan Pinhong Chen Guosheng Liu 

机构地区：[1]State Key Laboratory of Organometallics Chemistry, Shanghai Institute of Organic Chemistry Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2017年第6期876-880,共5页中国化学（英文版）

基　　金：We are grateful for financial support from the Na- tional Basic Research Program of China （No. 973-2015CB856600）, and the National Natural Science Foundation of China （Nos. 21225210, 21421091 and 21532009）.

摘　　要：A palladium-catalyzed oxidative vicinal diazidation of alkenes has been developed, in which TMSN3 was used as azide source. Both styrenes and unactivated alkenes are suitable for this reaction. And trans-alkyldiazides were obtained as major products from cyclic alkenes with moderate to good diastereoselectivities. This reaction afforded an efficient way for the synthesis of useful 1,2-diamines after hydrogenation.A palladium-catalyzed oxidative vicinal diazidation of alkenes has been developed, in which TMSN3 was used as azide source. Both styrenes and unactivated alkenes are suitable for this reaction. And trans-alkyldiazides were obtained as major products from cyclic alkenes with moderate to good diastereoselectivities. This reaction afforded an efficient way for the synthesis of useful 1,2-diamines after hydrogenation.

关 键 词：PALLADIUM-CATALYZED AZIDATION ALKENE STYRENE 

分 类 号：TQ325.1[化学工程—合成树脂塑料工业] O627.42[理学—有机化学]