表面活性肽的研究进展  

Research Progress in Surfactin

作　　者：李艳艳 张剑[1] Li Yanyan Zhang Jian(College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 03000)

机构地区：[1]山西大学化学化工学院,太原030006

出　　处：《化学通报》2017年第10期918-924,共7页Chemistry

基　　金：2016年度山西省重点研发计划国际合作项目(201603D421029)资助

摘　　要：表面活性肽(Surfactin)是由枯草芽孢杆菌(Bacillus subtilis)发酵产生的一系列具有相似基本结构的环状脂肽。与合成的表面活性剂相比,Surfactin的优势在于,其是以碳氢化合物等可再生能源为原料、采用微生物发酵技术产生的纯天然产品,具有表面活性大、环境无污染、易生物降解、抑菌作用良好等优异特性,符合现代绿色化学发展理念,在多个领域应用广泛。本文详细介绍了Surfactin的基本结构、主要特性、生产工艺、纯化方式以及应用,并对Surfactin下一步的研究工作进行了展望,为今后关于Surfactin的进一步研究提供了便利。Surfactin belongs to biosurfactant. It is a series of cyclic lipopeptides with similar basic structures produced by fermentation of Bacillus subtilis. Compared with synthetic surfactant,surfactin has following advantages：（ 1） It is a natural product produced by microbial fermentation technology using renewable energy such as hydrocarbon;（ 2） It has high surface activity,no pollution to the environment,easy to biodegrade,good antibacterial effect and other excellent features;（ 3） It is consistent with the modern concept of the development of green chemistry,and used in a wide range of applications. In this paper,the basic structure,main characteristics,production process,purification methods and application of surfactin were reviewed in detail,and the research prospect on surfactin is discussed,which could facilitate the further study of surfactin.

关 键 词：生物表面活性剂 SURFACTIN 微生物发酵 环状脂肽 

分 类 号：TQ423[化学工程] TQ929[轻工技术与工程—发酵工程]