蛋氨酸对宫内发育迟缓断奶仔猪血浆生化指标和肠道消化吸收功能的影响  

Effects of methionine on plasma biochemical parameters and intestinal digestive and absorptive function in intrauterine growth-retarded weanling piglets

作　　者：苏伟鹏[1] 张昊[1] 应志雄[1] 李悦[1] 周乐[1] 张莉莉[1] 王恬[1] 

机构地区：[1]南京农业大学动物科技学院,江苏南京210095

出　　处：《食品工业科技》2017年第19期298-303,共6页Science and Technology of Food Industry

基　　金：国家自然科学基金(31572418);江苏高校优势学科建设工程二期项目

摘　　要：目的:研究蛋氨酸对宫内发育迟缓(IUGR)断奶仔猪血浆生化指标和肠道消化吸收功能的调节作用。方法:所有仔猪于21 d龄断奶,30头正常出生体重(NBW)断奶仔猪饲喂基础日粮(NBW-CON组),60头IUGR断奶仔猪随机分成两个处理组,分别饲喂基础日粮(IUGR-CON组)和添加0.12%蛋氨酸的实验日粮(IUGR-MET组),每个处理组6个重复,每个重复5头猪,实验期为28 d。结果:与NBW-CON断奶仔猪相比,IUGR-CON断奶仔猪血浆尿素氮含量显著升高(p<0.05),血浆总蛋白和D-木糖含量显著降低(p<0.05)。IUGR-CON断奶仔猪粗蛋白和总能表观消化率、空肠食糜胰蛋白酶活性、黏膜碱性磷酸酶和Na+-K+-ATP酶活性均显著降低(p<0.05)。与IUGR-CON断奶仔猪相比,IUGR-MET断奶仔猪血浆尿素氮含量显著降低(p<0.05),血浆D-木糖含量显著升高(p<0.05)。日粮添加0.12%蛋氨酸显著缓解IUGR介导断奶仔猪粗蛋白表观消化率、空肠食糜胰蛋白酶活性和黏膜Na+-K+-ATP酶活性降低(p<0.05)。结论:日粮添加0.12%蛋氨酸可降低IUGR断奶仔猪血浆尿素氮含量,并在一定程度上缓解了IUGR对断奶仔猪肠道消化吸收功能的不良影响。Objective：The aim of this study was to investigate the effects of methionine on plasma biochemical parameters and intestinal digestive and absorptive function in weanling piglets with intrauterine growth retardation （ IUGR ）. Methods ： After weaning（21 d of postnatal age）, thirty female normal birth weight（NBW） piglets were assigned to receive the control diet （NBW-CON） ,and sixty same-sex IUGR piglets were randomly assigned to receive the control diet（IUGR-CON） or the control diet supplemented with 0.12% methionine （IUGR-MET）for 28 d, each group consisted of six replicates with five piglets per replicate.Results：Compared with NBW-CON piglets, the plasma urea nitrogen content of piglets in IUGR-CON group was increased,whereas the plasma total protein and D- xylose contents were significantly decreased （p 〈 0.05 ）. In addition, the apparent digestibility of crude protein and gross energy, the activity of trypsin in the jejunal digesta, and the activities of alkaline phosphatase and Na^＋ -K^＋ -ATPase in the jejunal mucosa of piglets in IUGR-CON group were also significantly decreased（p 〈 0.05 ）.Compared with piglets in IUGR-CON group, IUGR-MET piglets had decreased plasma urea nitrogen content,whereas increased plasma D-xylose content （p 〈 0.05 ）.Dietary supplementation of 0.12% methionine significantly alleviated the decreased apparent digestibility of crude protein,the activity of trypsin in jejunal digesta, and the activity of Na^＋ - K^＋ - ATPase in jejunal mucosa （p 〈 0.05 ）. Conclusion ： Dietary supplementation of 0.12 % methionine significantly decreased plasma urea nitrogen content and partially improved digestive and absorptive function in the intestine of IUGR weanling piglets.

关 键 词：蛋氨酸 宫内发育迟缓 断奶仔猪 肠道 消化吸收功能 

分 类 号：TS201.4[轻工技术与工程—食品科学]