丘脑梗死患者的情绪记忆改变  

Characteristics of emotional memory in patients with thalamic infarction

作　　者：刘晓亭 朱幼玲 席春华 唐敏 

机构地区：[1]安徽医科大学第三附属医院合肥市第一人民医院神经内科,合肥230061

出　　处：《中华行为医学与脑科学杂志》2017年第9期838-842,共5页Chinese Journal of Behavioral Medicine and Brain Science

摘　　要：目的探讨不同侧别丘脑梗死患者（thalamic infarction，TI）的情绪记忆改变及不同情绪效价对丘脑梗死患者的记忆影响特征。方法使用正性、中性及负性效价的情绪图片分别对28例TI患者（TI组）和28例与之相匹配的无脑部病变住院患者（对照组）进行情绪记忆学习-再认任务测试。结果（1）学习阶段，两组的正性情绪图片识别成绩差异无统计学意义（P〉0．05）。与对照组情绪图片的中性和负性识别成绩相比，TI组成绩均明显下降[对照组：中性（12．96±1．62）分；负性（13．57±1．37）分，TI组：中性（10．79±2．07）分；负性（10．96±2．05）分]，均差异有统计学意义（分别为中性t=-4．5；负性t=-5．6，均P〈0．05）。（2）再认阶段，TI组[（36．14±3．24）分]总情绪图片再认正确得分较对照组[（41．89±3．43）分]明显下降，差异有统计学意义（t=-6．44，P〈0．05）；TI组[正性（10．93±1．96）分；中性（11．25±1．67）分]与对照组[正性（14．04±1．29）分；中性（13．68±1．56）分]正性和中性图片再认得分相比，差异有统计学意义（正性t=-7．00；中性t=5．61，均P〈0．05）；两组负性图片再认得分差异无统计学意义（P〉0．05）。（3）左侧丘脑梗死组（LTI）[（34．43±3．48）分]总情绪图片再认正确得分较右侧丘脑梗死组（RTI）[（37．86±1．83）分]明显下降，差异有统计学意义（t=3．26，P〈0．05）；LTI组[（10．43±1．55）分]中性图片再认得分较RTI组[（12．07±1．38）分]明显下降，差异有统计学意义（t=2．95，P〈0．05）。结论TI患者可能依赖不同的神经机制，影响不同效价的情绪记忆环路过程。不同侧别丘脑梗死患者的情绪记忆受损严重程度不同，左侧丘脑对记忆的影响更大。Objective To investigate the emotional memory changes in patients with thalamic infarction on different laterals and explore the impact of different emotional valence pictures on the thalamic infarction（TI） patients＇ memory. Methods 28 patients with thalamic infarction（TI group）and 28 patients who were hospitalized without TI during the same period （ control group） were given emotional memory test, a test where they use their emotional memory to evaluate and recognize pictures with different emotional valence, including positive, neutral, and negative valence. Results （ 1 ） At the stage of evaluating emotional images, there were no significant difference between patients with TI and control group in positive evaluation （P〉0.05） .Compared with control group （neutral（12.96±1.62） ,negative（13.57±1.37） ,respectively） ,neutral and negative recognition scores for emotional pictures of patients with TI（ neutral（ 10.79±2.07）, negative （ 10.96± 2.05 ）, respectively） were decreased significantly （ positive t = - 4.5 and negative t = - 5.6, both P〈 0.05 ）. （2） At the stage of emotional images memorizing tests ,TI group＇ s total scores on re-accessing total emotional pictures were significantly lower than those in control group （ （36.14 ± 3.24） vs （41.89 ± 3.43） respectively ） ） （ t= -6.44, P〈0.05 ）. Compared with control group （ positive （ 14.04± 1.29 ） , neutral （ 13.68± 1.56） ）, patients with TI（ positive（ 10.93± 1.96）, neutral（ 11.25± 1.67） ） were decreased significantly in the emotional pictures memorizing tests （t=-7.00,5.61, P〈0.05 ）. But there were no difference in negative stimulus between the two groups （P〉0.05）. （3）The score of emotional pictures recognition in patients with LTI （34.43±3.48） were decreased significantly than that in patients with RTI（37.86±1.83） （t= 3.26, P〈0.05）. The score in recognizing neutral valence images in patients with LTI （10.43 ± 1.55 ） w

关 键 词：丘脑梗死 情绪记忆 神经心理测试 

分 类 号：R749.13[医药卫生—神经病学与精神病学]