复合营养素缓解视疲劳作用研究  

Effect of Compound Nutrients on Asthenopia

作　　者：吴昱含 张会图[1] 董淑珍 赵丽婷[2] WU Yu-han ZHANG Hui-tu DONG Shu-zhen ZHAO Li-ting(College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China Affiliated Hospital of Logistics University of PAP, Tianjin 300162, China)

机构地区：[1]天津科技大学生物工程学院,天津300457 [2]武警后勤学院附属医院,天津300162

出　　处：《食品与药品》2017年第5期314-317,共4页Food and Drug

摘　　要：目的研究以桑葚提取物、越橘提取物、叶黄素为主要成分的复合营养素改善视疲劳效果。方法选择具有视疲劳症状的受试者108人,采用随机、双盲、安慰剂对照设计,将全部受试对象分为试食组和对照组两组。试食组服用复合营养素,对照组服用安慰剂。60 d后,测定其功效性指标及安全性指标。结果试食组试食前后自身比较及试食后与对照组比较症状总积分明显改善(P<0.001);试食后症状总有效23例,总有效率42.6%,与对照组比较差异有高度统计学意义(P<0.001);试食组明视持久度试食前后自身比较,及试食后与对照组比较均差异有高度统计学意义(P<0.001)。试食前后试食组与对照组视力和用眼时间均没有明显改变。安全性指标测定均正常。结论复合营养素有缓解视疲劳功能的作用,安全无副作用。Objective To study the function of compound nutrients mainly composed of mulberry extract, bilberry extract and lutein on asthenopia. Methods 108 subjects with eye-fatigue were selected and divided into trial group or control group by the randomized double-blind method. The functional and safety indices were measured after taking compound nutrients or placebo respectively for 60 days. Results The symptom score of the trial group after experiment was significantly alleviated compared with that of the trial group before experiment and the control group （P〈0.001, respectively）. Symptoms of 23 subjects in the trial group were improved, and the total effective rate in the trial group was 42.6 %, which was significantly higher than that of the control group. Visuognosis persistence of the trial group after experiment were significantly improved compared with that of the trial group before experiment and the control group （P〈0.001, respectively）. Both intra-group comparison and intergroup comparison before and after the experiment showed no significant difference in visual acuity and eye using time. The safety indicators of the subjects were normal. Conclusion The compound nutrients can obviously relieve the symptoms of asthenopia without side effect.

关 键 词：视疲劳 桑葚提取物 越橘提取物 叶黄素 

分 类 号：R151.3[医药卫生—营养与食品卫生学]