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作 者:ZHANGMEILAN YUANCHANGYAN 等
机构地区:[1]ShanghaiInstituteofCellBiology,ChineseAcademyofSciences,320Yo-yangRoad,Shanghai200031,China [2]ShanghaiI
出 处:《Cell Research》1997年第1期51-59,共9页细胞研究(英文版)
摘 要:Epidermal growth factor (EGF) is produced primarily by Leydig cells of human testis. Expression of the EGF gene was assessed in mouse testis during the course of sexual maturation by the application of the RT-PCR method and the use of specific oligonucleotide primers. Testis EGF mRNA content increased with the developmental age of the mice, i.e., day 15 < day 30 < day 45 postnatal. The expression of the EGF gene appears to correlate with maturation of the testis and proliferation of Leydig cells.
关 键 词:Epidermal growth factor TESTIS gene expression SPERMATOGENESIS sexual maturation
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