麒麟菜中溴酚化合物的提取和降血糖活性  

Extraction and Hypoglycemic Activity of Bromophenols Compounds from Eucheuma muricatum

作　　者：安婷婷[1] 李玲娜[1] 王鹤[1] 

机构地区：[1]海南省药物研究所,海南海口570311

出　　处：《安徽农业科学》2017年第32期138-139,177,共3页Journal of Anhui Agricultural Sciences

基　　金：海南省自然科学基金项目(211014)

摘　　要：[目的]从麒麟菜中提取溴酚化合物。[方法]以海洋红藻类麒麟菜为原料,采用50%甲醇、50%乙醇、50%丙酮超声提取和95%乙醇、60%乙醇和50%乙醇浸提的方法,最后评价提取物和分离后组分的体外降血糖活性。[结果]50%乙醇浸提的效率最高,且提取物的降血糖活性高达73%,且氯仿∶甲醇=100∶0组分活性最高,达70%。[结论]为进一步开发海南经济藻类及新的降血糖药物提供了依据。[Objective]The aim was to extract bromine phenolic compounds from Eucheuma muricatum.[Method]The marine red alga Eucheuma was taken as raw materials,and 50% methanol,50% ethanol and 50% acetone ultrasonic extraction and 95% ethanol,60% ethanol and 50%ethanol leaching method were used. Finally,the in vitro hypoglycemic activities of final evaluation extracts and isolated group were evaluated.[Result] The efficiency of ethanol extraction was the highest in 50% ethanol extracts,and the blood glucose activity of the extracts was 73%,and the activity of chloroform-methanol(100∶ 0) was the highest,reaching 70%. [Conclusion] The results provide theoretical basis for further development of Hainan economic algae and new hypoglycemic agent.

关 键 词：海洋红藻 麒麟菜 溴酚化合物 降血糖活性 

分 类 号：S-3[农业科学]