氧化锌纳米颗粒抗菌活性在医学中的应用及研究进展  

Application and research progress of antimicrobial activity of zinc oxide nanoparticles in medicine

作　　者：王靖宇[1] 杜乐乐[1] 王婷[1] 王岩[1] 王秀梅[1] WANG Jingyu;DU Lele;WANG Ting;WANG Yah;WANG Xiumei.(Department of Stomatology,Second Affiliated Hospital,Harbin Med- ical University,Harbin 150086, China)

机构地区：[1]哈尔滨医科大学附属第二医院牙体牙髓科,黑龙江哈尔滨150086

出　　处：《口腔医学》2017年第11期1045-1048,共4页Stomatology

基　　金：黑龙江省领军人才梯队后备带头人资助项目([2013]575);哈尔滨市科技局科技创新人才资助项目(2016RAXYJ094)

摘　　要：氧化锌纳米颗粒(Zinc oxide nanoparticles,Zn O-NPS)是一种多功能性的新型无机材料,其颗粒大小约在1~100 nm。由于晶粒的细微化,其表面电子结构和晶体结构发生变化,具有高透明度、高分散性等特点。近年来随着对Zn O-NPS抗菌作用的深入研究,其在医学领域的应用逐渐增加,该文针对Zn O-NPS的抗菌作用在医学中的应用作一综述与展望。Zinc oxide nanoparticles is a versatile new inorganic material,the particle size of which is about 1 ~ 100 nm. Because of the fineness of particles,the surface electronic structure and crystal structure have changed,and the surface effect,the macroscopic objects do not have the volume effect,quantum size effect and macroscopic tunnel effect,with high transparency,high dispersion and other characteristics. In recent years,with the in-depth study of nano-zinc oxide antibacterial effect,its application in the medical field has gradually increased. In this paper,the antimicrobial effect of nano-zinc oxide in medical application was reviewed and prospected.

关 键 词：氧化锌纳米颗粒 抗菌活性 抗菌机制 应用 

分 类 号：R780.2[医药卫生—口腔医学]