Determination of action potential wavelength restitution in Scn5a^＋/- mouse hearts modelling human Brugada syndrome  

作　　者：Gary Tse Sheung Ting Wong Vivian Tse Jie Ming Yeo 

机构地区：[1]School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China [2]Faculty of Medicine, Imperial College, London, UK [3]Department of Physiology, McGill University, Canada

出　　处：《Journal of Geriatric Cardiology》2017年第9期595-596,共2页老年心脏病学杂志（英文版）

摘　　要：Brugada syndrome is a primary electrical disorder of theheart, predisposing affected individuals to potentially lethal,ventricular tachy-arrhythmias. A number of mechanismshave been identified as being important increasing the riskof these rhythms. Wavelength （γ） restitution has beensuggested to predict the onset of action potential duration（APD） alternans in mouse Scn5a^＋/- hearts modelling Bru-gada syndrome.

关 键 词：Action potential DURATION Conduction DEPOLARIZATION RESTITUTION REPOLARIZATION WAVELENGTH 

分 类 号：R[医药卫生]