烟雾病遗传学研究  

Genetic study on moyamoya disease

作　　者：周丽 王乔树[1] ZHOU Li;WANG Qiao-shu(Department of Neurology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 200080, Chin)

机构地区：[1]上海交通大学附属第一人民医院神经内科,200080

出　　处：《中国现代神经疾病杂志》2017年第12期929-932,共4页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：国家自然科学基金资助项目(项目编号:81371304)~~

摘　　要：烟雾病是一种慢性进行性、闭塞性脑血管病,其病因和发病机制目前尚未阐明。近年来国内外大量研究证实其存在遗传易感性,且遗传性因素在发病机制中的作用较获得性因素更加重要。本文就近年来烟雾病遗传学研究进展进行综述,以为早期诊断和有效精准治疗提供指导。Moyamoya disease （MMD） is a chronic progressive obstructive cerebrovascular disease. At present, the etiology and pathogenesis of MMD are still not clear. Recently, many studies confirmed the genetic susceptibility of MMD and reported that the genetic factors are more important than acquired causes. We summarize the domestic and foreign studies on the genetics of MMD, and expect to provide a guidance for earlv diagnosis and nrecise treatment.

关 键 词：脑底异常血管网病 基因 遗传学 综述 

分 类 号：R743[医药卫生—神经病学与精神病学]