脑-机接口技术在脑卒中后上肢运动功能恢复中的研究进展  

Research progress of brain-computer interface technology for the rehabilitation of the upper limb motor function after stroke

作　　者：王慧 王春方[1] 孙长城[1] 陈龙[3] 顾斌[3] 明东[3] 杜金刚[1] 

机构地区：[1]天津市人民医院康复医学科,天津市康复医学研究所,300121 [2]天津体育学院健康与运动科学系,300381 [3]天津大学精密仪器与光电子工程学院,300072

出　　处：《国际生物医学工程杂志》2017年第5期389-392,F0003,共5页International Journal of Biomedical Engineering

基　　金：天津市卫计委科技攻关项目（14KG107）;天津市中医药重点领域项目（2017009）

摘　　要：脑卒中后,上肢功能障碍发生率高且恢复困难,严重影响患者日常生活能力和生活质量.脑卒中通常因神经组织损伤而导致运动、感觉、认知等多方面损伤,有效的康复治疗可通过促进大脑残存神经的重塑来提高功能与能力.作为一种现代智能神经康复技术,脑-机接口（BCI）在大脑与周围环境之间直接建立交流通道,通过提取大脑的神经活动信息,转化为驱动外部设备的命令,而不依赖于外周神经系统和肌肉组织.BCI技术非常适合用于神经康复训练,通过BCI的反馈并利用其外接设备进行反复训练,可诱导产生正常的运动模式,间接诱导更为正常的大脑信号产生,促进大脑重塑,提高患者运动能力及运动控制水平.从BCI技术作用原理及其在上肢运动功能康复中的应用、疗效、存在问题等方面对BCI技术在卒中后上肢运动功能恢复中的研究作一综述.The upper limb dysfunction resulted from stroke has a high incidence and is hard to recover,seriously affecting the daily life and life quality of patients.The nerve tissue damage caused by stroke usually leads to the injuries of movement,sensory,cognitive and etc.The effective rehabilitation therapy can promote the rebuilding of the surviving cranial nerves to enhance the function and ability.As a modem intelligent nerve rehabilitation technology,brain-machine interface （BCI） directly builds the exchange channel between the brain and the surrounding environment.BCI extracts the brain＆#39;s neural activity information,and transfers into the command to drive external equipment.BCI does not rely on the peripheral nerve system and muscle tissue.BCI technology is well suited for neurological rehabilitation training,because the repeated training associated with external equipments and BCI feedback can induce a normal exercise mode,indirectly induced the generation of normal brain signal,and promote brain remodeling,so that improve the patient＆#39;s athletic ability and exercise control level.In this paper,the research progress of BCI technology for the rehabilitation of the upper limb motor function after stroke was reviewed,including the application,the efficacy and the existing limitations.

关 键 词：脑卒中 上肢运动功能恢复 脑-机接口 

分 类 号：R743.3[医药卫生—神经病学与精神病学] TP334.7[医药卫生—临床医学]