Review of Anemone Raddeana Rhizome and Its Pharmacological Effects  

作　　者：WANG Shu-ling ZHAO Zhen-kun SUN Jian-feng SUN Yun-ting PANG Xiao-qing ZENG Zhao-wu XIE Tian 

机构地区：[1]Medical College, Hangzhou Normal University, Hangzhou 311121, China [2]Suzhou Dongrui Pharmaceutical Co.,Ltd., Suzhou 215000, Jiangsu Province, China [3]Traditional Chinese Medicine College, Guangdong Pharmaceutical University, Guangzhou 511400, China [4]Department of Acupucture, Hangzhou Traditional Chinese Medicine Hospital,Hanazhou 311121 , China

出　　处：《Chinese Journal of Integrative Medicine》2018年第1期72-79,共8页中国结合医学杂志（英文版）

基　　金：Supported by the Natural Science Foundation of Zhejiang Province,China(No.LY16H270018)

摘　　要：The chemical compositions of Anemone raddeana Rhizome, a kind of traditional Chinese medicine, were reviewed, along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism, and is rich in triterpenoid saponins, most of which are pentacyclic, with oleanane as the nucleus. So far, 37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous, antimicrobial, anti-inflammatory, analgesic, antipyretic, anticonvulsive, antihistaminic, and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However, the herb also has hemolytic effects and can be toxic, which limits its clinical application. Further studies are needed on the pharmaceutical functions, mechanisms, and immunological responses to contribute to the herb＇s clinical applications.The chemical compositions of Anemone raddeana Rhizome, a kind of traditional Chinese medicine, were reviewed, along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism, and is rich in triterpenoid saponins, most of which are pentacyclic, with oleanane as the nucleus. So far, 37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous, antimicrobial, anti-inflammatory, analgesic, antipyretic, anticonvulsive, antihistaminic, and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However, the herb also has hemolytic effects and can be toxic, which limits its clinical application. Further studies are needed on the pharmaceutical functions, mechanisms, and immunological responses to contribute to the herb＇s clinical applications.

关 键 词：Anemone raddeana Rhizome phytochemical constituent pharmacological effect anticancerous antimicrobial ANTI-INFLAMMATORY ANALGESIC Chinese medicine 

分 类 号：R0[医药卫生]