膳食纤维对广州社区脑梗死患者及其高危人群常见危险因素的影响  

Effects of dietary fiber on common risk factors for cerebral infarction patients and high-risk population in Guangzhou communities

作　　者：赵秋革 方晓涛 叶凤仪 吴嘉茜 曾子淇 叶琛[3] 沈粤春[4] 田作军[1] 

机构地区：[1]广州医科大学附属第一医院神经内科,广东广州510120 [2]广州市番禺区市桥街北片社区卫生服务站,广东广州511400 [3]广州医科大学临床医学系,广东广州510182 [4]广州医科大学附属第一医院心内科,广东广州510120

出　　处：《广东医学》2018年第2期216-220,共5页Guangdong Medical Journal

基　　金：广东省科技计划项目(编号:2013B021800282;2014A020212350;2014A020212364);广州市科技计划项目(编号:201510010181)

摘　　要：目的探讨膳食纤维(DF)对广州社区脑梗死患者及其高危人群常见危险因素的影响。方法收集广州社区脑梗死患者及其高危人群180例,根据《膳食纤维食物频率调查表》及《中国食物成分表》评估其DF摄入量。先将资料以DF 10 g和25 g为界分3组,与临床危险因素间进行单因素及多因素分析;再将资料分为有无高血压2个亚组,并分别以DF 20 g为界分为两组,比较两组间临床参数的差异。结果 DF<10 g的患者,其颈动脉斑块的Crouse评分高于10 g≤DF<25 g之间的患者(P=0.037);与DF≥25 g的患者相比亦呈增高趋势(P=0.06)。Ordinal回归发现,DF的3个分组间只有Crouse评分差异有统计学意义(Wald=4.459,P=0.035);其他参数均无统计学意义。另外,DF与Crouse评分呈负相关(r=-0.183,P=0.014)。高血压亚组中DF<20 g的患者总胆固醇(TC)及低密度脂蛋白(LDL)分别高于DF>20 g的患者(t=2.500,P=0.014;t=2.458,P=0.015);HBA1C亦呈降低趋势(t=1.943,P=0.055)。结论DF摄入减少是广州社区脑梗死患者及其高危人群颈动脉斑块形成的独立危险因素,更是该地区高血压患者血脂增高的危险因素。Objective To investigate the effects of dietary fiber （DF） on the common risk factors of patients with cerebral infarction and high -risk population in Guangzhou communities. Methods Totally 180 interviewees with cerebral infarction and high- risk population were collected from Guangzhou communities. The DF intake was estimated according to the ＂dietary fiber food frequency questionnaire＂ and the ＂Chinese food composition＂. The data was divided into three groups based on the cut - off points with DF of 10 g and 25 g. The univariate and multivariate analyses were carried out for assessment of clinical risk factors. Then the data was split into hypertension and non - hypertension subgroups, and further into group of DF 〉/20 g and group of DF 〈 20 g within the two subgroups, respectively, The clinical parameters were compared between DF I〉20 g and DF 〈 20 g groups. Results the Crouse score of carotid plaques of patients with DF 〈 10g was significantly higher than that of patients with DF10 -25g （P =0. 037） , and higher compared with patients of DF 〉 25 g though there was no significant difference revealed （ P = 0.06）. Ordinal regression showed that only Crouse score showed statistical significance among the three DF groups （ Wald = 4. 459, P = 0. 035 ）. Additionally, DF was significantly negatively correlated with Crouse score （r = -0. 183, P = 0. 014）. In the hypertension subgroups, total cholesterol and low density lipoprotein were significantly higher in hypertension patients with DF 〈 20 g than those in hypertension patients with DF 〉 20 g （ t = 2, 500, P = 0. 014 ; t = 2. 458, P = 0. 015 ）. Conclusion The decrease of DF intake is not onlyan independent risk factor for carotid plaque formation in cerebral infarction patients and high - risk population in Guangzhou communities, but also a risk factor for high blood lipids in hypertensive patients in this region.

关 键 词：膳食纤维 脑梗死 危险因素 社区研究 

分 类 号：R743.33[医药卫生—神经病学与精神病学]