核桃多肽锌口服乳剂的制备工艺研究  

Studies on the Preparation Technology of Walnut Polypeptide Zinc Oral Emulsion

作　　者：吴悠[1,2] 曹聪 刘恒波 刘阳[1,2] 

机构地区：[1]武昌理工学院生命科学学院生物多肽糖尿病药物湖北省协同创新中心湖北省生物多肽糖尿病药物工程技术研究中心,武汉430223 [2]武汉工程大学化工与制药学院,武汉430073

出　　处：《食品工业》2018年第2期124-127,共4页The Food Industry

基　　金：湖北省高等学校优秀中青年科技创新团队计划项目(No.T201632),国家级大学生创新创业训练计划项目(No.201612310003,No.201612310004),武昌理工学院校级重点科研项目(No.2016K04),武昌理工学院校级科研项目(No.2016X07)

摘　　要：探索核桃多肽锌口服乳剂的制备工艺,开发核桃多肽新产品。根据口服乳剂的稳定性,以沉降容积比、乳析速度为指标选择适宜的复合乳化剂;利用干胶法,通过正交试验,确定乳剂的最佳制备工艺条件,并进行质量检查。结果表明:确定核桃多肽锌口服乳剂最佳配方为:大豆油、水与乳化剂质量比4∶2∶1,其中复合乳化剂的比例为:吐温80、阿拉伯胶与西黄耆胶质量比8∶1∶1;最优制备工艺为:70℃下以500 r/min搅拌30 min。该乳剂的配方设计合理,制备工艺简单,质量符合规定。It was to explore the preparation technology of walnut polypeptide zinc emulsion and to develop new products of walnut polypeptide. The suitable compound emulsifier was selected according to the stability of oral emulsion, with the index of sedimentation volume ratio and milk velocity. The dry gel method was used to prepare the emulsion, and the optimal preparation conditions of the emulsion were determined by orthogonal test. In addition, the quality of the emulsion was examined. The results showed that determination of walnut polypeptide zinc oral emulsion formula was as follows： the ratio of soybean oil, water and emulsifier was 4 ： 2 ： 1, the emulsifier ratio of Twain 80, Arabia gum and tragacanth was 8 ： 1 ： 1, and the optimal preparation method of the emulsion was 30 min for 500 r/min at 70 ℃ with stirring. The formula design of the walnut polypeptide zinc oral emulsion was reasonable, the preparation technology was simple, and the quality was consistent with the regulation.

关 键 词：核桃多肽 锌 乳剂 

分 类 号：TQ464.7[化学工程—制药化工]