506例精神分裂症患者脑血流改变分析  

Analysis of Cerebral Blood Flow on 506 Schizophrenics

作　　者：关念红[1] 张晋碚[1] 赵伟琳 陈月英[1] 唐济湘[1] 殷晓鹏[3] 廖亚勇[3] 杨志英[3] 

机构地区：[1]中山医科大学附属三院精神科,广州市510630 [2]广西区人民医院 [3]中山医科大学

出　　处：《中国超声医学杂志》2002年第8期593-594,共2页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨精神分裂症患者的大脑血流特点。方法 :应用经颅多普勒超声血流分析仪 (TCD)对 5 0 6名患者进行大脑血管血流测定 ,并与正常组进行对照比较分析。结果 :精神分裂症的 TCD血流异常占 5 5 .5 3%。基动脉的 Vs、 Vd,左大脑中动脉的 Vs,两侧大脑后动脉的 Vd增高 ;两侧椎动脉的 Vs,左大脑前动脉的 Vs、 Vd,右大脑前动脉的 Vs和两侧大脑后动脉的 Vs减低。结论 :精神分裂症的脑血流有异常 。Objective:To explore the cerebral blood flow features with schizophrenic patients.Methods:Transcranial Doppler ultrasonography was performed on 506 schizophrenics and 135 control subjects to detect the velocity of cerebral blood flow.Results:The abnormal rate of TCD in schizophrenics was 55 53%.Vs and Vd of basilar artery,Vs of left middle cerebral artery and Vd of posterior cerebral artery were increased.Vs of vertebral artery,Vs and Vd of left anterior cerebral artery,Vs of right anterior cerebral artery and Vs of posterior cerebral artery were decreased.Conclusions:There is abnormal cerebral blood flow in schizophrenics.To use the cerebral metabolism drug may help to get rehabilitation of schizophrenic patients.

关 键 词：脑血流 精神分裂症 经颅多普勒超声 血管扩张 

分 类 号：R749.3[医药卫生—神经病学与精神病学]