鱼鳞病样蕈样肉芽肿1例  

A Case of Ichthyosiform Mycosis Fungoides

作　　者：苏蓓蓓[1,2] 王涛[1] 刘跃华[1] 晋红中[1] 方凯[1] SU Beibei , WANG Tao, LIU Yuehua, JIN Hongzhong, FANG Kai(Department of Dematology , Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College ,Beijing 100730, China ; Department of Dermatology, Central Hospital of Xinxiang, Xinxiang 453000, Chin)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院皮肤科,北京100730 [2]新乡市中心医院皮肤科,河南新乡453000

出　　处：《中国皮肤性病学杂志》2018年第4期423-425,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者男,20岁。全身多发鱼鳞状斑片,皮肤粗糙、发红1年半。查体见躯干、四肢皮肤干燥、粗糙,泛发大小不等褐色菱形或多角形鱼鳞状斑片,可见多发红斑、脱屑。右颈、双侧腹股沟可触及数个约黄豆大小淋巴结。皮损组织病理示:角化过度及灶状角化不全,棘细胞内水肿,少量单个异型淋巴细胞移入表皮,真皮浅层血管周围少量淋巴组织细胞浸润。免疫组织化学示:浸润细胞CD3、CD4、CD45RO阳性。诊断鱼鳞病样蕈样肉芽肿。A 20-year-old male presented with scaly patches that was dry, rough and reddish all over the body for one and a half years.Physical examination revealed extensive irregular brown rhombic or polygonal scaly patches and diffused scaly erythema on his limbs and trunk.The bean-size lymph nodes were palpable in the right cervical and bilateral inguinal section.The histopathologic examination showed hyperkeratosis,focal parakeratosis,epidermotropic infiltration of atypical lymphocytes and slight lymphocytes and histiocytes infiltration around the vessels in the superficial dermis.Immunohistochemical stain showed that CD3,CD4 and CD45RO were positive to the atypical lymphocytes.The diagnosis of ichthyosiform mycosis fungoides was made according to the clinical manifestations,histopathological and immunohistochemical changes.

关 键 词：蕈样肉芽肿 鱼鳞病样 皮肤T细胞淋巴瘤 

分 类 号：R739.5[医药卫生—肿瘤]