Iron, Dopamine, and α-Synuclein Interactions in at-Risk Dopaminergic Neurons in Parkinson's Disease  

作　　者：Ning Song Junxia Xie 

机构地区：[1]Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, Medical College of Qingdao University [2]Institute of Brain Science and Disease, Qingdao University

出　　处：《Neuroscience Bulletin》2018年第2期382-384,共3页神经科学通报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(81430024,31771124,31571054,and 31371081);Excellent Innovative Team of Shandong Province and Taishan Scholars Construction Project

摘　　要：Parkinson’s disease(PD)is recognized as the second most common neurodegenerative disorder after Alzheimer disease.Although a fascinating 200-year journey of research has revealed the multifaceted nature of PD[1,2],its fundamental features are the loss of dopaminergic neurons in the substantia nigra pars compacta(SNpc)and depletion of dopamine(DA)in the striatum.Iron accumulates in normal brains with aging.Such

关 键 词：In Synuclein Interactions in at-Risk Dopaminergic Neurons in Parkinson’s Disease and DOPAMINE 

分 类 号：R[医药卫生]