仔猪断奶应激对肠道功能和组织结构影响的研究  

Effects of piglets weaning stress on intestine development and histomorphology

作　　者：于光辉[1] 姜建阳[1] 王西彤 张华杰 耿梅[1] 宋春阳[1] YU Guang-hui;JIANG Jian-yang;WANG Xi-tong;ZHANG Hua-jie;GENG Mei;SONG Chun-yang(College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 255109, China;Animal diseases and control ＆ prevention center of Weihai City, weihai 264200, China)

机构地区：[1]青岛农业大学动物科技学院,山东青岛266109 [2]威海市动物疾病控制预防中心,山东威海264200

出　　处：《中国兽医杂志》2018年第2期23-26,29,共5页Chinese Journal of Veterinary Medicine

基　　金：青岛农业大学高层次人才科研基金(6631114311);国家自然科学基金(31601924);山东省现代农业产业技术体系生猪创新团队(SDAIT-08-08)

摘　　要：为了研究仔猪断奶应激对肠道功能和组织结构的影响,试验选择不同抗应激能力的莱芜猪和杜长大(DLY)商品仔猪各10头作为研究对象,分别于断奶前1周(21 d)、断奶当天(28 d)、断奶后1 d(29 d)、断奶后1周(35 d)、断奶后2周(42 d)5个阶段,测定十二指肠和空肠的消化酶活性、肠绒毛组织发育的变化。试验结果表明,两品种仔猪断奶后1周莱芜猪胰蛋白酶含量和活性比杜长大仔猪分别高81.48%(P<0.01)和21.44%(P<0.01);两品种仔猪的十二指肠肠绒毛长度在断奶后1周都比断奶前变短(P<0.05),断奶后1周莱芜猪的十二指肠和空肠肠绒毛长度比杜长大分别长73.62%(P<0.01)和65.63%(P<0.01)。莱芜猪比杜长大有更高的消化酶活性和肠道组织修复能力,具有更强的抗断奶应激的能力。This experiment was performed to investigate the impact of weaning on Laiwu piglets and DLY piglets and assess their weaning anti-stress capabilities. A total of 20 piglets were used in this study. Digestive enzyme activity, intestinai villus histomor- phology and microflora were also analyzed. The Laiwu piglets trypsin content and activity were 81.48% （P 〈0. 01） and 21.44% （ P 〈0.01 ） greater than those of DLY at 1 week post-weaning. The duodenal villus length of both breeds was shorter at 1 week post- weaning than that during pre-weaning （ P 〈 0.05 ）, The Laiwu piglets＇ duodenal and jejunum villus length were 73.62% （ P 〈 0.01 ） and 65.63% （ P 〈0.01 ） higher than DLY at 1 week post weaning. The Laiwu piglets have greater digestive enzyme activity, and intestinal repair ability than DLY to cope with weaning stress.

关 键 词：杜长大 肠道发育 莱芜猪 断奶应激 

分 类 号：S858.28[农业科学—临床兽医学]