大枣多糖铁口服液的制备及品质研究  

Preparation and Quality Research of the Jujube Polysaccharide Iron Oral Solution

作　　者：徐华容[1,2] 唐志玮 王涛 刘恒和 姚少成 阮金兰[1,2,3] XU Huarong;TANG Zhiwei;WANG Tao;LIU Henghe;YAO Shaocheng;RUAN Jinlan(School of Life Science, Wuchang University of Technology （Wuhan 430223;School of Chemical Engineering ＆ Pharmacy, Wuhan Institute of Technology （Wuhan 430073;Tongji Medical College, Huazhong University of Science and Technology （Wuhan 430030)

机构地区：[1]武昌理工学院生命科学学院,武汉430223 [2]武汉工程大学化工与制药学院,武汉430073 [3]华中科技大学同济医学院,武汉430030

出　　处：《食品工业》2018年第5期87-89,共3页The Food Industry

摘　　要：为制备大枣多糖铁口服液制剂,并对其稳定性进行研究,通过超声辅助热水浸提法提取大枣多糖,纯化后与三氯化铁反应合成大枣多糖铁配合物,经除杂过程后得到精制的大枣多糖铁,取2 g溶于80 m L超纯水中,加入0.03%的4-羟基苯甲酸乙酯(羟苯乙酯)作为防腐剂,灭菌即得大枣多糖铁口服液。结果表明,制得的大枣多糖铁口服液稳定性好,简单易得。该制备工艺简单易行,方法可靠,制剂品质稳定。To prepare the jujube polysaccharide iron oral liquid,and to research its stability,the polysaccharide was extracted from the jujube polysaccharide by ultrasonic assisted hot water extraction.After purification,the polysaccharide was used to synthesize the polysaccharide iron complex with ferric chloride.Get the refined jujube polysaccharide iron after impurity removal process,and then 2 g refined jujube polysaccharide iron was taken to dissolve in 80 m L ultrapure water,and 0.03% of ethyl 4-hydroxybenzoate（hydroxyphenethyl） was added as preservative.The Jujube polysaccharide iron oral solution was prepared after the sterilization.Results showed that the jujube polysaccharide iron oral liquid had good stability and was easy to obtain.The preparation process was simple and easy.The method was reliable,and the preparation quality was stable.

关 键 词：大枣多糖铁 口服液 制备 防腐剂 

分 类 号：TQ464[化学工程—制药化工]