Photosensitive peptide hydrogels as smart materials for applications  

作　　者：Dongdong Wu Xian Xie Adnan A.Kadi Yan Zhang 

机构地区：[1]State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University [2]Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University

出　　处：《Chinese Chemical Letters》2018年第7期1098-1104,共7页中国化学快报（英文版）

基　　金：the financial support from the National Natural Science Foundation of China(Nos. 21572102, 21672103,21302093);the International Scientific Partnership Program ISPP at King Saud University for funding the research work through ISPP#0101

摘　　要：Photosensitive peptide hydrogels(PPHs) which allow photo-modulation on the self-assembly of peptides were broadly developed over the recent decades. The real-time and spatial modulation of hydrogel properties upon non-contact light illumination, allow the PPHs serving as super "smart" soft materials.Herein, we briefly summarized the PPHs preparing from the integration of diverse photosensitive moieties with peptides through gelation abilities, "smart" manner and applications. Moreover, a novel type of PPHs based on intramolecular biorthogonal photo-click reaction developed by our group has been demonstrated with relative mechanism and applications.Photosensitive peptide hydrogels(PPHs) which allow photo-modulation on the self-assembly of peptides were broadly developed over the recent decades. The real-time and spatial modulation of hydrogel properties upon non-contact light illumination, allow the PPHs serving as super "smart" soft materials.Herein, we briefly summarized the PPHs preparing from the integration of diverse photosensitive moieties with peptides through gelation abilities, "smart" manner and applications. Moreover, a novel type of PPHs based on intramolecular biorthogonal photo-click reaction developed by our group has been demonstrated with relative mechanism and applications.

关 键 词：Photosensitive hydrogel PEPTIDE SELF-ASSEMBLY Smart materials TETRAZOLE 

分 类 号：TB381[一般工业技术—材料科学与工程] TQ427.26[化学工程]