高效液相色谱法测定食品模拟物中偏苯三甲酸酐的含量  

Determination of the concentration of trimellitic anhydride in food simulants by high performance liquid chromatography

作　　者：何媛媛 李威 潘祥华 刘桂华 窦晓 吴泽颖 张玉 HE Yuan-Yuan;LI Wei;PAN Xiang-Hua;LIU Gui-Hua;DOU Xiao;WU Ze-Ying;ZHANG Yu(Changzhou Import and Export Industry and Consumer Product Safety Testing Center, Changzhou 213000, China;School of Mathematical Science and Chemical Engineering, Changzhou Institute of Technology, Changzhou 213000, China)

机构地区：[1]常州进出口工业及消费品安全检测中心,常州213000 [2]常州工学院数理与化工学院,常州213000

出　　处：《食品安全质量检测学报》2018年第13期3441-3447,共7页Journal of Food Safety and Quality

基　　金：原江苏省出入境检验检疫局项目(2018KJ03)~~

摘　　要：目的建立高效液相色谱法测定5种食品模拟物中偏苯三甲酸酐迁移量的分析方法。方法以4%(V:V)乙酸溶液、10%(V:V)乙醇溶液、20%(V:V)乙醇溶液、50%(V:V)乙醇溶液、橄榄油分别模拟酸性、水性、酒精类以及油脂类食品,通过高效液相色谱法(high performance liquid chromatography HPLC)测定食品模拟物中的偏苯三甲酸的含量,采用外标法定量,计算出偏苯三甲酸酐的迁移量。结果各模拟物中加标回收率为96.7%~104.0%,相对标准偏差为0.2%~3.7%,水基食品模拟物中该方法的检出限和定量限分别为0.2、0.5 mg/L,橄榄油食品模拟物中该方法的检出限和定量限分别为0.2、0.5 mg/kg。结论该方法具有良好的准确度和精密度,可以准确测定各种食品接触材料中偏苯三甲酸酐的迁移量。Objective To establish a method for the determination of concentration of trimellitic anhydride in food simulants by high performance liquid chromatography.Methods The 4%（V：V） acetic acid solution,10%（V：V） ethanol solution,20%（V：V） ethanol solution,50%（V：V） ethanol solution,and olive oil were used to simulate acid,water,and alcohol,respectively.The content of trimellitic acid in the food simulants were determined by high performance liquid chromatography（HPLC） and quantified by external standard method to calculate the migration amount of trimellitic anhydride.Results The recoveries were 96.7%-104.0%,the relative standard deviations were 0.2%-3.7%,and the limits of detection and quantification in water-based food simulants were 0.2 mg/L and 0.5 mg/L,respectively.The detection limit and quantitation limits of the method in olive oil food simulants were 0.2 mg/L and 0.5 mg/kg,respectively.Conclusion This method has good accuracy and precision,which can accurately determine the migration amount of trimellitic anhydride in various food contacting materials.

关 键 词：高效液相色谱法 食品接触材料 偏苯三甲酸酐 迁移量 偏苯三甲酸 基质匹配 

分 类 号：O657.72[理学—分析化学] TS201.6[理学—化学]