先天性肾上腺皮质增生症儿童注意缺陷多动障碍行为研究  

A behavior study of attention deficit hyperactivity disorder in children with congenital adrenal hyperplasia

作　　者：胡啸 张星星[2] HU Xiao;ZHANG Xingxing(Department of Pediatrics,The First Hospital of Changsha,Changsha,Hunan 410005,China;Department of Pediatrics,The Secorwl Xiangya Hospital of Central South University,Changsha,Hunan 410013,China)

机构地区：[1]长沙市第一医院儿科,湖南长沙410005 [2]中南大学湘雅二医院儿科,湖南长沙410013

出　　处：《安徽医药》2018年第11期2150-2153,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的研究先天性肾上腺皮质增生症(CAH)患儿注意缺陷多动障碍行为,初步探讨先天性肾上腺皮质增生症患儿行为问题成因。方法采用病例对照研究方法,选取31例2014年1月至2015年10月中南大学湘雅二医院及长沙市第一医院儿科门诊就诊先天性肾上腺皮质增生症患儿(CAH组)及31例性别年龄匹配健康儿童(对照组)。采用Conners父母量表(PSQ)评估儿童注意缺陷多动障碍行为问题。应用SPSS 19.0统计进行数据统计分析。结果 CAH组平均品行问题(0.730±0.395)分、学习问题(0.806±0.611)分、身心障碍(0.219±0.265)分、冲动多动(1.008±0.672)分及多动指数(0.890±0.508)均高于对照组,焦虑得分(0.379±0.280)分低于对照组。除学习问题外,其余项目均差异有统计学意义(P<0.05)。CAH组儿童仅身心障碍发生率(25.8%)高于对照组儿童(3.2%),差异有统计学意义(χ~2=4.679,P=0.031)。结论 CAH儿童存在行为的问题,同时包括外向性行为问题和内向性行为问题,但外向性行为问题更为普遍。Objective To investigate behavior of attention deficit hyperactivity disorder in children with congenital adrenal hyperplasia（ CAH） and to preliminarily study the cause of behavior problems. Methods Thirty-one children patients with CAH in Department of Pediatrics,The First Hospital of Changsha and The Second Xiangya Hospital of Central South University from January 2014 to October2015 were selected as CAH group and 31 cases of age and sex matched healthy children were selected as control group by case-control study. The attention deficit hyperactivity disorder behavioral problems were evaluated by Conners parent symptom questionnaire（ PSQ）.Statistical analysis was performed by SPSS 19. 0 statistical software. Results The average conduct（ 0. 730 ± 0. 395）,learning problems（ 0. 806 ± 0. 611）,physical and mental disorders（ 0. 219 ± 0. 265）,impulsive hyperactivity（ 1. 008 ± 0. 672） and hyperactivity index（ 0. 890 ± 0. 508） in the CAH group were higher than those in the control group,and the score of anxiety（ 0. 379 ± 0. 280） was lower than that of the control group. Except for learning problems,the others have difference statistically significant（ P〈0. 05）. The incidence of physical and mental disorders in CAH group（ 25. 8%） was higher than that in control group（ 3. 2%）. The difference was statistically significant（ χ^2= 4. 679,P = 0. 031）. Conclusion Children with CAH have behavior problems including extravert behavior problems and introvert behavior problems,but extravert problems were more common.

关 键 词：先天性肾上腺皮质增生症 注意缺陷多动障碍 Conners父母量表 

分 类 号：R749.94[医药卫生—神经病学与精神病学]