硫化氢对线粒体损伤后氧化呼吸链影响的研究进展  

Advances in studies on the effect of hydrogen sulfide on oxidative respiratory chain after mitochondrial injury

作　　者：梁琰 李毅[2] Liang Yan;Li Yi(Qinghai University,Xining 810016,China;Department of Burns and Plastic Surgery,Affiliated Hospital of Qinghai University,Xining 810001,China)

机构地区：[1]青海大学,西宁810016 [2]青海大学附属医院烧伤整形科,西宁810001

出　　处：《中华损伤与修复杂志（电子版）》2018年第5期383-385,共3页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)

基　　金：国家自然科学基金(81660320)

摘　　要：探讨硫化氢对线粒体损伤后氧化呼吸链的影响。已有研究证实,硫化氢在线粒体损伤后有保护氧化呼吸链,稳定细胞色素C氧化酶活性及氧化磷酸化反应的作用,进而保证ATP的生成。通过对比国内相关研究,就硫化氢对线粒体损伤后氧化呼吸链的影响,归纳其作用机制,为今后硫化氢的进一步研究提供相关的理论基础。To investigate the effect of hydrogen sulfide on oxidative respiratory chain after mitochondrial injury. Studies have confirmed that hydrogen sulfide protects the oxidative respiratory chain after mitochondrial injury, stabilizing cytochrome C oxidase activity and oxidative phosphorylation, thereby ensuring the production of ATP. By comparing the related studies in China, the effect of hydrogen sulfide on the oxidative respiratory chain after mitoehondrial injury and its meehanism of action was summarized in this paper, providing a theoretical basis for the further study of hydrogen sulfide in the future.

关 键 词：硫化氢 线粒体疾病 电子转运 

分 类 号：R363[医药卫生—病理学]