Making Spiroketal-based Diphosphine （SKP） Ligands via a Catalytic Asymmetric Approach  

作　　者：Xiaoming Wang Kuiling Ding 

机构地区：[1]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), 345 Lingling Road, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2018年第10期899-903,共5页中国化学（英文版）

摘　　要：The spiro concept for chiral ligand design represents an important contribution to the area of asymmetric catalysis. Due to the considerable difficulties in the construction of enantiopure all-carbon spiro backbones, the development of catalytic asymmetric synthesis of chiral spiro structures via short steps is highly valuable. Herein we present our studies on the catalytic asymmetric synthesis of aromatic spiroketals and the corresponding diphos- phine （SKP） ligands.The spiro concept for chiral ligand design represents an important contribution to the area of asymmetric catalysis. Due to the considerable difficulties in the construction of enantiopure all-carbon spiro backbones, the development of catalytic asymmetric synthesis of chiral spiro structures via short steps is highly valuable. Herein we present our studies on the catalytic asymmetric synthesis of aromatic spiroketals and the corresponding diphos- phine （SKP） ligands.

关 键 词：chiral ligand spiro compounds SPIROKETAL asymmetric catalysis HYDROGENATION 

分 类 号：O643.36[理学—物理化学]