70岁以上帕金森病患者的丘脑底核深部脑刺激  

Subthalamic nucleus deep brain stimulation in Parkinson disease patients over age 70 years

作　　者：Russmann H. Ghika J. Villemure J.- G. F.J.G. Vingerhoets 姚庆和 

机构地区：[1]Service de Neurologie- BH 13, CHUV, CH1011 Lausanne, Switzerland Dr.

出　　处：《世界核心医学期刊文摘（神经病学分册）》2005年第4期47-47,共1页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：The effects of subthalamic nucleus deep brain stimulation were studied in 52 consecutive patients (13 over age 70, 15 under age 60, 24 age 60 to 70). All groups had improvement of motor fluctuations and dyskinesia. Patients over age 70 had worsening of Unified Parkinson’ s Disease Rating Scale motor scores on medication, despite less medication reduction. Their activities of daily living and axial subscores worsened, particularly in those with preoperative gait difficulties.The effects of subthalamic nucleus deep brain stimulation were studied in 52 consecutive patients (13 over age 70, 15 under age 60, 24 age 60 to 70). All groups had improvement of motor fluctuations and dyskinesia. Patients over age 70 had worsening of Unified Parkinson’ s Disease Rating Scale motor scores on medication, despite less medication reduction. Their activities of daily living and axial subscores worsened, particularly in those with preoperative gait difficulties.

关 键 词：丘脑底核 帕金森病 深部脑刺激 日常生活能力 运动评分 运动障碍 轴向运动 药物治疗 等级量表 

分 类 号：R742.5[医药卫生—神经病学与精神病学]