I型毛发-鼻-指(趾)综合征发生纵向V形甲营养不良  

V- shaped, longitudinal nail dystrophies in trichorhinophalangeal syndrome type I

作　　者：Itin P.H. Eich G. Fistarol S.K. 刘安 

机构地区：[1]Department of Dermatology, Kantonsspital Aarau, CH- 5001 Aarau, Switzerland

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2005年第12期3-3,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Trichorhinophalangeal syndrome (TRPS) is a rare genodermatosis with growth retardation, craniofacial abnormalities, alopecia and brachyphalangia. Three subtypes with considerable clinical overlap can be separated. Numerous nail changes have been documented in this syndrome. We observed a 19- year- old female with typical TRPS I who developed unique V- shaped longitudinal nail dystrophies on both hands. TRPS belongs to the spectrum of ectodermal dysplasias, and therefore it is not surprising that cutaneous adnexal structures are involved in different ways.Trichorhinophalangeal syndrome (TRPS) is a rare genodermatosis with growth retardation, craniofacial abnormalities, alopecia and brachyphalangia. Three subtypes with considerable clinical overlap can be separated. Numerous nail changes have been documented in this syndrome. We observed a 19- year- old female with typical TRPS I who developed unique V- shaped longitudinal nail dystrophies on both hands. TRPS belongs to the spectrum of ectodermal dysplasias, and therefore it is not surprising that cutaneous adnexal structures are involved in different ways.

关 键 词：甲营养不良 遗传性皮肤病 秃发 生长发育迟缓 皮肤附属器 外胚层发育不良 双手指甲 病谱 文献报道 

分 类 号：R758.5[医药卫生—皮肤病学与性病学]