1例短肠综合征患儿发生内源性乙醇发酵  

Endogenous ethanol fermentation in a child with short bowel syndrome

作　　者：Jansson- Nettelbladt E. Meurling S. Petrini B. Sjlin J. 李开 

机构地区：[1]Department of Clinical Microbiology, Karolinska University Hospital, Solna, SE- 171 76 Stockholm, Sweden

出　　处：《世界核心医学期刊文摘（儿科学分册）》2006年第A10期12-12,共1页

摘　　要：The term “ auto- brewery syndrome” has been frequently used to describe patients who show features of alcohol intoxication because of abnormal yeast proliferation after ingesting carbohydrate- rich meals. We present a case of a 3- y- old girl with short bowel syndrome (SBS) who demonstrated signs of alcohol intoxication on repeated occasions. A blood test indicated an ethanol concentration of 15 mmol/l, and cultures from gastric fluid and faeces showed the presence of Candida kefyr. An association was found between the introduction of a carbohydrate- rich fruit drink and the occurrence of symptoms. Conclusion: The possibility of endogenous ethanol fermentation should be considered in patients with SBS and the diagnosis of auto- brewery syndrome added to the differential diagnosis list for D- lactic acidosis. Management includes both antifungal treatment and special diet modification.The term “ auto- brewery syndrome” has been frequently used to describe patients who show features of alcohol intoxication because of abnormal yeast proliferation after ingesting carbohydrate- rich meals. We present a case of a 3- y- old girl with short bowel syndrome (SBS) who demonstrated signs of alcohol intoxication on repeated occasions. A blood test indicated an ethanol concentration of 15 mmol/l, and cultures from gastric fluid and faeces showed the presence of Candida kefyr. An association was found between the introduction of a carbohydrate- rich fruit drink and the occurrence of symptoms. Conclusion: The possibility of endogenous ethanol fermentation should be considered in patients with SBS and the diagnosis of auto- brewery syndrome added to the differential diagnosis list for D- lactic acidosis. Management includes both antifungal treatment and special diet modification.

关 键 词：短肠综合征 乙醇发酵 内源 酒精中毒 粪便培养 抗真菌药 乳酸中毒 异常增殖 果汁饮料 酒精浓度 

分 类 号：R726.5[医药卫生—儿科]