结直肠癌患者饮食结构特征及与健康人群的差异分析  

Diet pattern characterization and analysis between colorectal cancer patients and healthy volunteers

作　　者：高仁元[1] 吴磊 黄林生[1] 潘成[1] 尹明明[1] 李豪[1] 孔程[1] 沈蓉蓉[1] 张鹏[1] 秦环龙[1] Gao Renyuan;Wu Lei;Huang Linsheng;Pan Cheng;Yin Mingming;Li Hao;Kong Cheng;Shen Rongrong;Zhang Peng;Qin Huanlong(Department of General Surgery, Shanghai Tenth People Hospital affiliated to Tongji University School of Medicine, Shanghai 200072, China;Department of General Surgery,Shanghai Luodian Hospital, Shanghai 201908, China)

机构地区：[1]同济大学附属第十人民医院普外科,上海200072 [2]上海市罗店医院普外科,201908

出　　处：《中华结直肠疾病电子杂志》2017年第2期102-107,共6页Chinese Journal of Colorectal Diseases(Electronic Edition)

基　　金：国家自然科学基金资助项目(No.81230057;No.81472262;No.81302066);上海市市级医院新兴前沿技术联合攻关项目(No.SHDC12012106)

摘　　要：目的研究结直肠癌患者与健康人群的饮食结构差异。方法采用饮食频次调查表收集40例肠癌患者和72例正常人群饮食信息,根据饮食成分表各食物营养成分,使用Mann-Whitney U检验计算宏量营养素和微量营养素摄入量,分析二者之间的差异。结果结直肠癌患者能量摄入量显著高于健康人群(Z=-2.836,P=0.005),碳水化合物和脂肪的摄入量也显著高于对照组人群(Z=-2.065,P=0.018;Z=-2.368,P=0.039)。此外,微量元素中胡萝卜素、硫胺素、核黄素以及维生素E也显著高于对照组人群。经过年龄和性别校正后,不同水平脂肪的摄入量与结直肠癌具有相关性(Wald=9.658,P=0.02)。结论结直肠癌患者饮食结构与健康人群有显著差异,特别是以高能量、高蛋白和高脂肪为特点,而关于脂肪摄入量与结直肠癌的风险则需要更大样本量研究。Objective To study the difference of diet pattern between colorectal cancer patientsand healthy volunteer.Methods Food Frequency Questionnaire was applied to obtain the diet data of40colorectal cancer patients and72healthy volunteers.Then daily intake of macronutrients and micronutrientswere calculated and compared between the two groups.Results The energy intake was significantlyhigher in colorectal cancer patients than the healthy volunteers(Z=-2.836,P=0.005),the intake of proteinand carbohydrates in the colorectal cancer patients were also significant high than the healthy(Z=-2.065,P=0.018;Z=-2.368,P=0.039).In addition,colorectal cancer patients also took more carotene,thiamine,riboflavin than healthy volunteers.And after adjustment for age and gender,fat intake with different intakeamounts was associated with colorectal cancer(Wald=9.658,P=0.02).Conclusion The diet pattern ofcolorectal cancer patients,which characterized by high intake of energy,protein and fat,was significantdifferent from healthy volunteers.However,in terms of the relationship between fat intake and colorectalcancer risk,it is still needed a large sample size survey.

关 键 词：结直肠肿瘤 基本饮食 饮食结构 频次调查表 脂肪摄入量 

分 类 号：R735.34[医药卫生—肿瘤]